BDBM50063581 CHEMBL3398612
SMILES NC[C@H]1CC[C@@H](CC1)C(=O)N[C@@H](Cc1ccccc1)c1nc(c(Cl)[nH]1)-c1ccc2c(N)n[nH]c2c1
InChI Key InChIKey=JOQPSWPCSAWTEY-PGKZFUBTSA-N
Data 12 KI
Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB
Found 12 hits for monomerid = 50063581
Affinity DataKi: 0.310nMAssay Description:Competitive inhibition of human coagulation factor 11a assessed as reduction in release of p-nitroaniline after 10 to 120 mins by Michaelis-Menten eq...More data for this Ligand-Target Pair
Affinity DataKi: 0.310nMAssay Description:Inhibition of human coagulation factor 11a at 25 degCMore data for this Ligand-Target Pair
Affinity DataKi: 1.5nMAssay Description:Binding affinity to coagulation factor 11a (unknown origin) assessed as inhibition constant using (p-Glu-Pro-Arg-pNa,HCl) as substrate preincubated f...More data for this Ligand-Target Pair
Affinity DataKi: 5nMAssay Description:Inhibition of plasma kallikrein (unknown origin)More data for this Ligand-Target Pair
Affinity DataKi: 23nMAssay Description:Inhibition of human trypsin at 25 degCMore data for this Ligand-Target Pair
Affinity DataKi: 650nMAssay Description:Inhibition of tissue kallikrein (unknown origin)More data for this Ligand-Target Pair
Affinity DataKi: 4.22E+3nMAssay Description:Inhibition of coagulation factor 7a (unknown origin)More data for this Ligand-Target Pair
Affinity DataKi: 6.39E+3nMAssay Description:Inhibition of coagulation factor 10a (unknown origin)More data for this Ligand-Target Pair
Affinity DataKi: 8.40E+3nMAssay Description:Inhibition of plasmin (unknown origin)More data for this Ligand-Target Pair
Affinity DataKi: >1.26E+4nMAssay Description:Inhibition of thrombin (unknown origin)More data for this Ligand-Target Pair
Affinity DataKi: >2.20E+4nMAssay Description:Inhibition of TPA (unknown origin)More data for this Ligand-Target Pair
Affinity DataKi: >3.49E+4nMAssay Description:Inhibition of coagulation factor 9a (unknown origin)More data for this Ligand-Target Pair