BDBM50063746 2-Phenylamino-benzo[d][1,3]oxazin-4-one::CHEMBL9945::CVD-0010838::MAT-POS-ea426761-13

SMILES O=c1oc(Nc2ccccc2)nc2ccccc12

InChI Key InChIKey=UUMLXNZZKFQMMR-UHFFFAOYSA-N

Data  1 KI  4 IC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
Find this compound or compounds like it in BindingDB:
   Substructure
Similarity at least:  must be >=0.5
Exact match

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 5 hits for monomerid = 50063746   

TargetReplicase polyprotein 1ab(2019-nCoV)
Israel Institution of Biological Research

LigandPNGBDBM50063746(2-Phenylamino-benzo[d][1,3]oxazin-4-one | CHEMBL99...)
Affinity DataIC50: 363nMAssay Description:The assay was performed according to the published procedure. Briefly, compounds were seeded into assay-ready plates (Greiner 384PP, cat# 781280) usi...More data for this Ligand-Target Pair
In Depth
Date in BDB:
11/5/2021
Entry Details Article

TargetReplicase polyprotein 1ab(2019-nCoV)
Israel Institution of Biological Research

LigandPNGBDBM50063746(2-Phenylamino-benzo[d][1,3]oxazin-4-one | CHEMBL99...)
Affinity DataIC50: 1.57E+3nMAssay Description:Compounds were seeded into assay-ready plates (Greiner 384 low volume, cat. no. 784900) using an Echo 555 acoustic dispenser, and dimethyl sulfoxide ...More data for this Ligand-Target Pair
In Depth
Date in BDB:
11/27/2023
Entry Details
PubMed
TargetReplicase polyprotein 1ab(2019-nCoV)
Israel Institution of Biological Research

LigandPNGBDBM50063746(2-Phenylamino-benzo[d][1,3]oxazin-4-one | CHEMBL99...)
Affinity DataIC50: 1.57E+3nMAssay Description:Compounds were seeded into assay-ready plates (Greiner 384 low volume, cat 784900) using an Echo 555 acoustic dispenser, and DMSO was back-filled for...More data for this Ligand-Target Pair
In Depth
Date in BDB:
11/5/2021
Entry Details Article

TargetNeutrophil elastase(Human)
Syntex Research

Curated by ChEMBL
LigandPNGBDBM50063746(2-Phenylamino-benzo[d][1,3]oxazin-4-one | CHEMBL99...)
Affinity DataKi:  1.00E+4nMAssay Description:Component deacylation rate constant for interaction with human leukocyte elastaseMore data for this Ligand-Target Pair
In Depth
Date in BDB:
5/19/2013
Entry Details Article
PubMed
TargetComplement C1r subcomponent(Human)
Warner-Lambert

Curated by ChEMBL
LigandPNGBDBM50063746(2-Phenylamino-benzo[d][1,3]oxazin-4-one | CHEMBL99...)
Affinity DataIC50: 6.25E+4nMAssay Description:Inhibition of 50% of human C1r Serine Protease by initially using Cbz-Gly-Arg-S-Bzl as substrateMore data for this Ligand-Target Pair
In Depth
Date in BDB:
11/10/2009
Entry Details Article
PubMed