BDBM50063983 5-((4-phenoxyphenylamino)methyl)furo[2,3-d]pyrimidine-2,4-diamine::5-[(4-Phenoxy-phenylamino)-methyl]-furo[2,3-d]pyrimidine-2,4-diamine::CHEMBL23297

SMILES Nc1nc(N)c2c(CNc3ccc(Oc4ccccc4)cc3)coc2n1

InChI Key InChIKey=MOYSYRUJUOJUNH-UHFFFAOYSA-N

Data  8 IC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
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Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 8 hits for monomerid = 50063983   

TargetBifunctional dihydrofolate reductase-thymidylate synthase(Toxoplasma gondii)
Duquesne University

Curated by ChEMBL
LigandPNGBDBM50063983(5-((4-phenoxyphenylamino)methyl)furo[2,3-d]pyrimid...)
Affinity DataIC50:  3.24E+4nMAssay Description:Inhibitory activity against dihydrofolate reductase from Toxoplasma gondiiMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetDihydrofolate reductase(Pneumocystis carinii)
Duquesne University

Curated by ChEMBL
LigandPNGBDBM50063983(5-((4-phenoxyphenylamino)methyl)furo[2,3-d]pyrimid...)
Affinity DataIC50:  8.10E+3nMAssay Description:Inhibitory activity against dihydrofolate reductase from pneumocystis carniiMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetDihydrofolate reductase(Rattus norvegicus (rat))
Duquesne University

Curated by ChEMBL
LigandPNGBDBM50063983(5-((4-phenoxyphenylamino)methyl)furo[2,3-d]pyrimid...)
Affinity DataIC50:  1.62E+4nMAssay Description:Inhibitory activity against dihydrofolate reductase from rat liverMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetBifunctional dihydrofolate reductase-thymidylate synthase(Toxoplasma gondii)
Duquesne University

Curated by ChEMBL
LigandPNGBDBM50063983(5-((4-phenoxyphenylamino)methyl)furo[2,3-d]pyrimid...)
Affinity DataIC50:  3.24E+4nMAssay Description:Inhibition of Toxoplasma gondii DHFR by spectrophotometric assayMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetDihydrofolate reductase(Rattus norvegicus (rat))
Duquesne University

Curated by ChEMBL
LigandPNGBDBM50063983(5-((4-phenoxyphenylamino)methyl)furo[2,3-d]pyrimid...)
Affinity DataIC50:  1.62E+4nMAssay Description:Inhibition of rat liver dihydrofolate reductaseMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetBifunctional dihydrofolate reductase-thymidylate synthase(Toxoplasma gondii)
Duquesne University

Curated by ChEMBL
LigandPNGBDBM50063983(5-((4-phenoxyphenylamino)methyl)furo[2,3-d]pyrimid...)
Affinity DataIC50:  3.24E+4nMAssay Description:Inhibition of Toxoplasma gondii dihydrofolate reductaseMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetDihydrofolate reductase(Rattus norvegicus (rat))
Duquesne University

Curated by ChEMBL
LigandPNGBDBM50063983(5-((4-phenoxyphenylamino)methyl)furo[2,3-d]pyrimid...)
Affinity DataIC50:  1.62E+4nMAssay Description:Inhibition of rat liver DHFR by spectrophotometric assayMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetDihydrofolate reductase(Pneumocystis carinii)
Duquesne University

Curated by ChEMBL
LigandPNGBDBM50063983(5-((4-phenoxyphenylamino)methyl)furo[2,3-d]pyrimid...)
Affinity DataIC50:  8.10E+3nMAssay Description:Inhibition of Pneumocystis carinii dihydrofolate reductaseMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed