BDBM50064482 2-demethylthiocolchicine::CHEMBL277239::N-((S)-2-hydroxy-1,3-dimethoxy-10-methylsulfanyl-9-oxo-5,6,7,9-tetrahydro-benzo[a]heptalen-7-yl)-acetamide::N-(2-Hydroxy-1,3-dimethoxy-10-methylsulfanyl-9-oxo-5,6,7,9-tetrahydro-benzo[a]heptalen-7-yl)-acetamide

SMILES COc1cc2CC[C@H](NC(C)=O)c3cc(=O)c(SC)ccc3-c2c(OC)c1O

InChI Key InChIKey=OMQLBXIHBJAOIO-HNNXBMFYSA-N

Data  2 IC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
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Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 2 hits for monomerid = 50064482   

TargetTubulin alpha-1A chain(Sus scrofa (Pig))
University Of North Carolina At Chapel Hill

Curated by ChEMBL
LigandPNGBDBM50064482(2-demethylthiocolchicine | CHEMBL277239 | N-((S)-2...)
Affinity DataIC50:  1.51E+3nMAssay Description:Inhibition of tubulin polymerization interacting at the colchicine binding site.More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetTubulin beta-1 chain(Homo sapiens (Human))
University Of North Carolina

Curated by ChEMBL
LigandPNGBDBM50064482(2-demethylthiocolchicine | CHEMBL277239 | N-((S)-2...)
Affinity DataIC50:  1.50E+3nMAssay Description:Inhibitory concentration against tubulin assemblyMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed