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BDBM50064949 CHEMBL312631::N-(1-Benzyl-piperidin-4-yl)-2-(2-methoxy-phenyl)-acetamide

SMILES: COc1ccccc1CC(=O)NC1CCN(Cc2ccccc2)CC1

InChI Key: InChIKey=FSSMCNONYPJAGO-UHFFFAOYSA-N

Data: 1 KI

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Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 1 hit for monomerid = 50064949   
Target/Host
(Institution)
LigandTarget/Host
Links
Ligand
Links
Trg + Lig
Links
Ki
nM
ΔG°
kcal/mole
IC50
nM
Kd
nM
EC50/IC50
nM
koff
s-1
kon
M-1s-1
pHTemp
°C
Sigma non-opioid intracellular receptor 1


(Homo sapiens (Human))
BDBM50064949
PNG
(CHEMBL312631 | N-(1-Benzyl-piperidin-4-yl)-2-(2-me...)
Show SMILES COc1ccccc1CC(=O)NC1CCN(Cc2ccccc2)CC1
Show InChI InChI=1S/C21H26N2O2/c1-25-20-10-6-5-9-18(20)15-21(24)22-19-11-13-23(14-12-19)16-17-7-3-2-4-8-17/h2-10,19H,11-16H2,1H3,(H,22,24)
PDB

UniProtKB/SwissProt

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CHEMBL
PC cid
PC sid
UniChem

Similars

Article
PubMed
30.8n/an/an/an/an/an/an/an/a



Wake Forest University School of Medicine

Curated by ChEMBL


Assay Description
Binding affinity against sigma-1 receptor in guinea pig brain membranes using [3H]-(+)-pentazocine as the radioligand


J Med Chem 41: 2361-70 (1998)


Article DOI: 10.1021/jm980032l
BindingDB Entry DOI: 10.7270/Q2RN36Z5
More data for this
Ligand-Target Pair