BDBM50065041 1-Benzyl-1-[3-(2H-pyrazol-3-yl)-benzyl]-3-(2,4,6-trifluoro-phenyl)-urea::CHEMBL78870::FR-180734

SMILES Fc1cc(F)c(NC(=O)N(Cc2ccccc2)Cc2cccc(c2)-c2cc[nH]n2)c(F)c1

InChI Key InChIKey=GQGSSSROHBNTNO-UHFFFAOYSA-N

Data  3 IC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
Find this compound or compounds like it in BindingDB:
   Substructure
Similarity at least:  must be >=0.5
Exact match

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 3 hits for monomerid = 50065041   

TargetAcyl-CoA:cholesterol acyltransferase(Oryctolagus cuniculus)
Fujisawa Pharmaceutical

Curated by ChEMBL
LigandPNGBDBM50065041(1-Benzyl-1-[3-(2H-pyrazol-3-yl)-benzyl]-3-(2,4,6-t...)
Affinity DataIC50:  14nMAssay Description:In vitro inhibitory activity towards ACAT by the displacement of [1-14C]-oleolyl-CoA from the small intestine of cholesterol-fed rabbitsMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetAcyl-CoA:cholesterol acyltransferase(Oryctolagus cuniculus)
Fujisawa Pharmaceutical

Curated by ChEMBL
LigandPNGBDBM50065041(1-Benzyl-1-[3-(2H-pyrazol-3-yl)-benzyl]-3-(2,4,6-t...)
Affinity DataIC50:  14nMAssay Description:In vitro inhibitory activity against Acyl coenzyme A:cholesterol acyltransferase (ACAT) in rabbit intestinal microsomesMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetAcyl-CoA:cholesterol acyltransferase(Oryctolagus cuniculus)
Fujisawa Pharmaceutical

Curated by ChEMBL
LigandPNGBDBM50065041(1-Benzyl-1-[3-(2H-pyrazol-3-yl)-benzyl]-3-(2,4,6-t...)
Affinity DataIC50:  14nMAssay Description:In vitro inhibition of acyl coenzyme A:cholesterol acyltransferase (ACAT) from rabbit intestinal microsomesMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed