BDBM50065312 (Z)-4-methyl-3-(4-morpholinobenzylidene)indolin-2-one::4-Methyl-3-(4-morpholin-4-yl-benzylidene)-1,3-dihydro-indol-2-one::4-Methyl-3-[1-(4-morpholin-4-yl-phenyl)-meth-(Z)-ylidene]-1,3-dihydro-indol-2-one::CHEMBL90277
SMILES Cc1cccc2NC(=O)\C(=C/c3ccc(cc3)N3CCOCC3)c12
InChI Key InChIKey=KBPBXFBACWNRGQ-LGMDPLHJSA-N
Data 7 IC50
Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB
Found 7 hits for monomerid = 50065312
Affinity DataIC50: 2.09E+3nMAssay Description:Inhibitory activity against vascular endothelial growth factor receptor 2 (FLK1)More data for this Ligand-Target Pair
Affinity DataIC50: >1.00E+5nMAssay Description:Concentration required to achieve 50% inhibition of tyrosine phosphorylation on human Epidermal growth factor receptor (EGF RTK).More data for this Ligand-Target Pair
Affinity DataIC50: 2.10E+3nMAssay Description:Concentration required to achieve 50% inhibition of tyrosine phosphorylation on murine VEGF receptor (FLK-1 RTK).More data for this Ligand-Target Pair
TargetProto-oncogene tyrosine-protein kinase receptor Ret(Homo sapiens (Human))
University Of Milano-Bicocca
Curated by ChEMBL
University Of Milano-Bicocca
Curated by ChEMBL
Affinity DataIC50: 1.00E+5nMAssay Description:Inhibition of human recombinant His-tagged RET expressed in Sf9 insect cellsMore data for this Ligand-Target Pair
Affinity DataIC50: >1.00E+5nMAssay Description:Concentration required to achieve 50% inhibition of tyrosine phosphorylation on human Insulin-like growth factor I receptorMore data for this Ligand-Target Pair
Affinity DataIC50: 4.99E+4nMAssay Description:Test concentration required to achieve 50% inhibition of tyrosine phosphorylation on human Platelet-derived growth factor receptor beta (PDGF RTK).More data for this Ligand-Target Pair
Affinity DataIC50: 6.66E+4nMAssay Description:Concentration required to achieve 50% inhibition of tyrosine phosphorylation on human Her-2 receptor tyrosine kinase (HER-2 RTK)More data for this Ligand-Target Pair