BDBM50065773 CHEMBL97279::N-(9-Chloro-2-furan-2-yl-[1,2,4]triazolo[1,5-c]quinazolin-5-yl)-succinamic acid methyl ester

SMILES COC(=O)CCC(=O)Nc1nc2ccc(Cl)cc2c2nc(nn12)-c1ccco1

InChI Key InChIKey=KIFABODNEJDDQW-UHFFFAOYSA-N

Data  3 KI

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
Find this compound or compounds like it in BindingDB:
   Substructure
Similarity at least:  must be >=0.5
Exact match

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 3 hits for monomerid = 50065773   

TargetAdenosine receptor A2a(Rat)
National Institute of Diabetes

Curated by ChEMBL
LigandPNGBDBM50065773(N-(9-Chloro-2-furan-2-yl-[1,2,4]triazolo[1,5-c]qui...)
Affinity DataKi:  28.8nMAssay Description:Binding affinity was determined in radioligand binding assay at rat striatal Adenosine A2A receptor vs [3H]-CGS- 21680More data for this Ligand-Target Pair
In Depth
Date in BDB:
11/10/2009
Entry Details Article
PubMed
TargetAdenosine receptor A3(Human)
National Institute of Diabetes

Curated by ChEMBL
LigandPNGBDBM50065773(N-(9-Chloro-2-furan-2-yl-[1,2,4]triazolo[1,5-c]qui...)
Affinity DataKi:  55.1nMAssay Description:Binding affinity at cloned human adenosine A3 receptor expressed in HEK293 cells was determined using [125I]AB-MECA as radioligandMore data for this Ligand-Target Pair
In Depth
Date in BDB:
11/10/2009
Entry Details Article
PubMed
TargetAdenosine receptor A1(Rat)
National Institute of Diabetes

Curated by ChEMBL
LigandPNGBDBM50065773(N-(9-Chloro-2-furan-2-yl-[1,2,4]triazolo[1,5-c]qui...)
Affinity DataKi:  71.8nMAssay Description:Binding affinity was determined in radioligand binding assay at rat brain adenosine A1 receptor vs [3H]R-PIAMore data for this Ligand-Target Pair
In Depth
Date in BDB:
11/10/2009
Entry Details Article
PubMed