BDBM50065831 CHEMBL542913::N-[4-(2-Amino-3H-1lambda*4*-thiazol-4-yl)-phenyl]-acetamidine

SMILES CC(N)=Nc1ccc(cc1)-c1csc(N)n1

InChI Key InChIKey=JVLVVMCRAZSANQ-UHFFFAOYSA-N

Data  3 KI

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
Find this compound or compounds like it in BindingDB:
   Substructure
Similarity at least:  must be >=0.5
Exact match

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 3 hits for monomerid = 50065831   

TargetNitric oxide synthase, brain(Human)
Glaxo Wellcome Research and Development

Curated by ChEMBL
LigandPNGBDBM50065831(N-[4-(2-Amino-3H-1lambda*4*-thiazol-4-yl)-phenyl]-...)
Affinity DataKi:  7.50E+3nMAssay Description:Inhibitory activity against human neuronal nitric oxide synthase (nNOS) isoenzyme.More data for this Ligand-Target Pair
In Depth
Date in BDB:
11/7/2012
Entry Details Article
PubMed
TargetNitric oxide synthase, endothelial(Human)
Glaxo Wellcome Research and Development

Curated by ChEMBL
LigandPNGBDBM50065831(N-[4-(2-Amino-3H-1lambda*4*-thiazol-4-yl)-phenyl]-...)
Affinity DataKi: >5.00E+4nMAssay Description:Inhibitory activity against human endothelial nitric oxide synthase (eNOS) isoenzyme.More data for this Ligand-Target Pair
In Depth
Date in BDB:
11/7/2012
Entry Details Article
PubMed
TargetNitric oxide synthase, inducible(Human)
Glaxo Wellcome Research and Development

Curated by ChEMBL
LigandPNGBDBM50065831(N-[4-(2-Amino-3H-1lambda*4*-thiazol-4-yl)-phenyl]-...)
Affinity DataKi: >5.00E+4nMAssay Description:Inhibitory activity against human inducible nitric oxide synthase (iNOS) isoenzyme.More data for this Ligand-Target Pair
In Depth
Date in BDB:
11/7/2012
Entry Details Article
PubMed