BDBM50066292 CHEMBL109453::N-[3-Chloro-2-oxo-4-(3,4,5-trimethoxy-phenyl)-azetidin-1-yl]-2-hydroxy-benzamide

SMILES COc1cc(cc(OC)c1OC)C1C(Cl)C(=O)N1NC(=O)c1ccccc1O

InChI Key InChIKey=CWANEKNGPVYVPP-UHFFFAOYSA-N

Data  3 IC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
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Similarity at least:  must be >=0.5
Exact match

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 3 hits for monomerid = 50066292   

TargetIntegrase(Human immunodeficiency virus type 1)
National Cancer Institute-Bethesda

Curated by ChEMBL
LigandPNGBDBM50066292(N-[3-Chloro-2-oxo-4-(3,4,5-trimethoxy-phenyl)-azet...)
Affinity DataIC50: 6.88E+4nMAssay Description:Inhibitory concentration was evaluated as 50% inhibition of HIV-1 integrase enzyme at 3`- processing stage of DNA integration in experiment IMore data for this Ligand-Target Pair
In Depth
Date in BDB:
11/10/2009
Entry Details Article
PubMed
TargetIntegrase(Human immunodeficiency virus type 1)
National Cancer Institute-Bethesda

Curated by ChEMBL
LigandPNGBDBM50066292(N-[3-Chloro-2-oxo-4-(3,4,5-trimethoxy-phenyl)-azet...)
Affinity DataIC50: 7.37E+4nMAssay Description:Inhibitory concentration as 50% inhibition of HIV-1 integrase enzyme at strand transfer stage of DNA integration.More data for this Ligand-Target Pair
In Depth
Date in BDB:
11/10/2009
Entry Details Article
PubMed
TargetIntegrase(Human immunodeficiency virus type 1)
National Cancer Institute-Bethesda

Curated by ChEMBL
LigandPNGBDBM50066292(N-[3-Chloro-2-oxo-4-(3,4,5-trimethoxy-phenyl)-azet...)
Affinity DataIC50: 7.57E+4nMAssay Description:Inhibitory concentration was evaluated as 50% inhibition of HIV-1 integrase enzyme at 3`- processing stage of DNA integration in experiment IIMore data for this Ligand-Target Pair
In Depth
Date in BDB:
11/10/2009
Entry Details Article
PubMed