BDBM50066325 2-(2-Hydroxy-benzoyl)-4-[1-(4-methoxy-phenyl)-meth-(E)-ylidene]-5-methyl-2,4-dihydro-pyrazol-3-one::CHEMBL108031::CHEMBL433434

SMILES COc1ccc(C=c2c(=C)[nH]n(C(=O)c3ccccc3O)c2=O)cc1

InChI Key InChIKey=PLRZPJRARUHDBO-UHFFFAOYSA-N

Data  3 IC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
Find this compound or compounds like it in BindingDB:
   Substructure
Similarity at least:  must be >=0.5
Exact match

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 3 hits for monomerid = 50066325   

TargetIntegrase(Human immunodeficiency virus 1)
National Cancer Institute-Bethesda

Curated by ChEMBL
LigandPNGBDBM50066325(2-(2-Hydroxy-benzoyl)-4-[1-(4-methoxy-phenyl)-meth...)
Affinity DataIC50:  900nMAssay Description:Inhibition of HIV-1 integrase enzyme at 3`- processing stage of DNA integrationMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetIntegrase(Human immunodeficiency virus 1)
National Cancer Institute-Bethesda

Curated by ChEMBL
LigandPNGBDBM50066325(2-(2-Hydroxy-benzoyl)-4-[1-(4-methoxy-phenyl)-meth...)
Affinity DataIC50:  600nMAssay Description:Inhibitory activity against HIV-1 integraseMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetIntegrase(Human immunodeficiency virus 1)
National Cancer Institute-Bethesda

Curated by ChEMBL
LigandPNGBDBM50066325(2-(2-Hydroxy-benzoyl)-4-[1-(4-methoxy-phenyl)-meth...)
Affinity DataIC50:  600nMAssay Description:Inhibitory concentration as 50% inhibition of HIV-1 integrase enzyme at strand transfer stage of DNA integration.More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed