BDBM50066441 2-(2,6-Dimethyl-phenyl)-isoindole-1,3-dione::2-(2,6-dimethylphenyl)isoindoline-1,3-dione::CHEMBL8916

SMILES Cc1cccc(C)c1N1C(=O)c2ccccc2C1=O

InChI Key InChIKey=KDCNGAZTEPFIKL-UHFFFAOYSA-N

Data  6 IC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
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Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 6 hits for monomerid = 50066441   

TargetDipeptidyl peptidase 4(Homo sapiens (Human))
University Of Tokyo

Curated by ChEMBL
LigandPNGBDBM50066441(2-(2,6-Dimethyl-phenyl)-isoindole-1,3-dione | 2-(2...)
Affinity DataIC50: >3.98E+5nMAssay Description:Inhibitory activity against Dipeptidylpeptidase IV (DPP IV) in human acute lymphoblastic leukemia MOLT-4 cell lineMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetAminopeptidase N(Homo sapiens (Human))
University Of Tokyo

Curated by ChEMBL
LigandPNGBDBM50066441(2-(2,6-Dimethyl-phenyl)-isoindole-1,3-dione | 2-(2...)
Affinity DataIC50: >3.97E+5nMAssay Description:Inhibitory activity against aminopeptidase N (APN) in human acute lymphoblastic leukemia MOLT-4 cell lineMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetAminopeptidase N(Homo sapiens (Human))
University Of Tokyo

Curated by ChEMBL
LigandPNGBDBM50066441(2-(2,6-Dimethyl-phenyl)-isoindole-1,3-dione | 2-(2...)
Affinity DataIC50: >3.97E+5nMAssay Description:Inhibitory activity against aminopeptidase N assayed by the L-Ala-MCA method.More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetProstaglandin G/H synthase 2(Ovis aries (Sheep))
The University Of Tokyo

Curated by ChEMBL
LigandPNGBDBM50066441(2-(2,6-Dimethyl-phenyl)-isoindole-1,3-dione | 2-(2...)
Affinity DataIC50: <1nMAssay Description:Inhibitory activity (RA2) against Prostaglandin G/H synthase 2 was calculated relative to aspirinMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetProstaglandin G/H synthase 1(Ovis aries (Sheep))
The University Of Tokyo

Curated by ChEMBL
LigandPNGBDBM50066441(2-(2,6-Dimethyl-phenyl)-isoindole-1,3-dione | 2-(2...)
Affinity DataIC50: <1nMAssay Description:Inhibitory activity (RA1) against Prostaglandin G/H synthase 1 was calculated relative to aspirinMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetDipeptidyl peptidase 4(Homo sapiens (Human))
University Of Tokyo

Curated by ChEMBL
LigandPNGBDBM50066441(2-(2,6-Dimethyl-phenyl)-isoindole-1,3-dione | 2-(2...)
Affinity DataIC50: >3.98E+5nMAssay Description:Inhibitory activity against Dipeptidylpeptidase IV (DPP IV) in human acute lymphoblastic leukemia MOLT-4 cell lineMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed