BDBM50067002 (3R,6aS)-3-Allyl-2-oxo-hexahydro-furo[3,2-b]pyrrole-4-carboxylic acid benzyl ester::CHEMBL435213

SMILES C=CC[C@@H]1C2[C@H](CCN2C(=O)OCc2ccccc2)OC1=O

InChI Key InChIKey=AIOPERPCMDNFTR-GNXJLENFSA-N

Data  5 IC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
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Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 5 hits for monomerid = 50067002   

TargetNeutrophil elastase(Homo sapiens (Human))
Glaxowellcome Medicines Research Centre

Curated by ChEMBL
LigandPNGBDBM50067002((3R,6aS)-3-Allyl-2-oxo-hexahydro-furo[3,2-b]pyrrol...)
Affinity DataIC50:  47nMAssay Description:The compound was tested for inhibition of human neutrophil elastase enzyme with a preincubation time of 40 min.More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetCathepsin G(Homo sapiens (Human))
Glaxowellcome Medicines Research Centre

Curated by ChEMBL
LigandPNGBDBM50067002((3R,6aS)-3-Allyl-2-oxo-hexahydro-furo[3,2-b]pyrrol...)
Affinity DataIC50: >1.00E+5nMAssay Description:The compound was tested for inhibition of cathepsin G with a preincubation time of 15 min.More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetChymotrypsinogen A(Bos taurus (bovine))
Glaxowellcome Medicines Research Centre

Curated by ChEMBL
LigandPNGBDBM50067002((3R,6aS)-3-Allyl-2-oxo-hexahydro-furo[3,2-b]pyrrol...)
Affinity DataIC50:  1.59E+4nMAssay Description:The compound was tested for inhition of Chymotrypsinogen with a preincubation time of 15 minMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetNeutrophil elastase(Homo sapiens (Human))
Glaxowellcome Medicines Research Centre

Curated by ChEMBL
LigandPNGBDBM50067002((3R,6aS)-3-Allyl-2-oxo-hexahydro-furo[3,2-b]pyrrol...)
Affinity DataIC50:  336nMAssay Description:The compound was tested for inhibition of human neutrophil elastase enzyme with a preincubation time of 0 min.More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetProthrombin(Homo sapiens (Human))
Glaxowellcome Medicines Research Centre

Curated by ChEMBL
LigandPNGBDBM50067002((3R,6aS)-3-Allyl-2-oxo-hexahydro-furo[3,2-b]pyrrol...)
Affinity DataIC50:  4.90E+4nMAssay Description:The compound was tested for inhition of thrombin with a preincubation time of 15 minMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed