BDBM50067024 2-(3,4-Dihydroxy-benzylidene)-indan-1,3-dione::CHEMBL83598

SMILES [#8]-c1ccc(\[#6]=[#6]-2\[#6](=O)-c3ccccc3-[#6]-2=O)cc1-[#8]

InChI Key InChIKey=GQCXHTDRVKNGSA-UHFFFAOYSA-N

Data  3 IC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
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Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 4 hits for monomerid = 50067024   

TargetIntegrase(Human immunodeficiency virus type 1)
Sapienza University of Rome

Curated by ChEMBL
LigandPNGBDBM50067024(2-(3,4-Dihydroxy-benzylidene)-indan-1,3-dione | CH...)
Affinity DataIC50: 3.00E+3nMAssay Description:Compound concentration required to reduce HIV-1 Integrase 3'-processing activity by 50%More data for this Ligand-Target Pair
In Depth
Date in BDB:
11/8/2012
Entry Details Article
PubMed
TargetIntegrase(Human immunodeficiency virus type 1)
Sapienza University of Rome

Curated by ChEMBL
LigandPNGBDBM50067024(2-(3,4-Dihydroxy-benzylidene)-indan-1,3-dione | CH...)
Affinity DataIC50: 3.02E+3nMAssay Description:Inhibitory activity against HIV-1 Integrase (HIV-1-IN)More data for this Ligand-Target Pair
In Depth
Date in BDB:
5/20/2013
Entry Details Article
PubMed
TargetTyrosine-protein kinase Lck(Human)
R. W. Johnson Pharmaceutical Research Institute

Curated by ChEMBL
LigandPNGBDBM50067024(2-(3,4-Dihydroxy-benzylidene)-indan-1,3-dione | CH...)
Affinity DataIC50: 5.00E+3nMAssay Description:Inhibition of p56 Lck tyrosine kinaseMore data for this Ligand-Target Pair
In Depth
Date in BDB:
11/10/2009
Entry Details Article
PubMed
TargetArginase-1(Bovine)
Universite de Franche-Comte

Curated by ChEMBL
LigandPNGBDBM50067024(2-(3,4-Dihydroxy-benzylidene)-indan-1,3-dione | CH...)
Affinity DataIC50: 5.37E+5nMAssay Description:Inhibition of bovine liver arginase 1 using L-arginine as substrate incubated for 60 mins by OPA-p colorimetric assayMore data for this Ligand-Target Pair
In Depth
Date in BDB:
10/12/2025
Entry Details
PubMed