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BDBM50067086 3-Methyl-N-(3-pyridin-2-yl-isoquinolin-1-yl)-benzamidine::CHEMBL129373

SMILES: Cc1cccc(c1)C(N)=Nc1nc(cc2ccccc12)-c1ccccn1

InChI Key: InChIKey=IABRYYLROFPGTH-UHFFFAOYSA-N

Data: 1 KI

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Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 1 hit for monomerid = 50067086   
Target/Host
(Institution)
LigandTarget/Host
Links
Ligand
Links
Trg + Lig
Links
Ki
nM
ΔG°
kcal/mole
IC50
nM
Kd
nM
EC50/IC50
nM
koff
s-1
kon
M-1s-1
pHTemp
°C
Adenosine receptor A3


(Homo sapiens (Human))
BDBM50067086
PNG
(3-Methyl-N-(3-pyridin-2-yl-isoquinolin-1-yl)-benza...)
Show SMILES Cc1cccc(c1)C(N)=Nc1nc(cc2ccccc12)-c1ccccn1
Show InChI InChI=1S/C22H18N4/c1-15-7-6-9-17(13-15)21(23)26-22-18-10-3-2-8-16(18)14-20(25-22)19-11-4-5-12-24-19/h2-14H,1H3,(H2,23,25,26)
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PC cid
PC sid
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Similars

Article
PubMed
1.30E+6n/an/an/an/an/an/an/an/a



Vrije Universiteit

Curated by ChEMBL


Assay Description
Displacement of specific [125I]-AB-MECA binding at human adenosine A3 receptor expressed in HEK 293 cells.


J Med Chem 41: 3987-93 (1998)


Article DOI: 10.1021/jm980036q
BindingDB Entry DOI: 10.7270/Q2D21WR1
More data for this
Ligand-Target Pair