BDBM50067489 7-(2-Methoxy-benzyl)-2-(4-methoxy-phenyl)-3-methylaminomethyl-4-oxo-4,7-dihydro-thieno[2,3-b]pyridine-5-carboxylic acid ethyl ester::CHEMBL131751::ethyl 7-(2-methoxybenzyl)-2-(4-methoxyphenyl)-3-((methylamino)methyl)-4-oxo-4,7-dihydrothieno[2,3-b]pyridine-5-carboxylate

SMILES CCOC(=O)c1cn(Cc2ccccc2OC)c2sc(c(CNC)c2c1=O)-c1ccc(OC)cc1

InChI Key InChIKey=ROZBCYWIZSLLCF-UHFFFAOYSA-N

Data  2 IC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
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Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 2 hits for monomerid = 50067489   

TargetGonadotropin-releasing hormone receptor(Human)
Takeda Chemical Industries

Curated by ChEMBL
LigandPNGBDBM50067489(7-(2-Methoxy-benzyl)-2-(4-methoxy-phenyl)-3-methyl...)
Affinity DataIC50: 2.00E+3nMAssay Description:The Compound was tested for the concentration to inhibit 50% of [125 I ]leuprorelin binding to the cloned human Leutinizing releasing hormone recepto...More data for this Ligand-Target Pair
In Depth
Date in BDB:
11/8/2012
Entry Details Article
PubMed
TargetGonadotropin-releasing hormone receptor(Human)
Takeda Chemical Industries

Curated by ChEMBL
LigandPNGBDBM50067489(7-(2-Methoxy-benzyl)-2-(4-methoxy-phenyl)-3-methyl...)
Affinity DataIC50: 2.00E+3nMAssay Description:Inhibition of [125I]leuprorelin binding to human recombinant LHRH receptor expressed in CHO cellsMore data for this Ligand-Target Pair
In Depth
Date in BDB:
12/7/2012
Entry Details Article
PubMed