BDBM50067536 5-Hydroxy-2,4-dimethyl-8-[2'-(1H-tetrazol-5-yl)-biphenyl-4-ylmethyl]-8H-pyrido[2,3-d]pyrimidin-7-one::5-Hydroxy-2,4-dimethyl-8-[2'-(2H-tetrazol-5-yl)-biphenyl-4-ylmethyl]-8H-pyrido[2,3-d]pyrimidin-7-one::CHEMBL72838

SMILES Cc1nc(C)c2c(O)cc(=O)n(Cc3ccc(cc3)-c3ccccc3-c3nnn[nH]3)c2n1

InChI Key InChIKey=YROKAAIPBSCMJN-UHFFFAOYSA-N

Data  2 IC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
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Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 2 hits for monomerid = 50067536   

TargetType-1 angiotensin II receptor A/B(RAT)
Wyeth-Ayerst Research

Curated by ChEMBL
LigandPNGBDBM50067536(5-Hydroxy-2,4-dimethyl-8-[2'-(1H-tetrazol-5-yl)-bi...)
Affinity DataIC50:  0.170nMAssay Description:Compound was evaluated for the in vitro inhibition of specific binding of [125I]-A II to Angiotensin II receptor, type 1 from rat adrenal membranes.More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetType-1 angiotensin II receptor(Homo sapiens (Human))
Technische Universit£T Darmstadt

Curated by ChEMBL
LigandPNGBDBM50067536(5-Hydroxy-2,4-dimethyl-8-[2'-(1H-tetrazol-5-yl)-bi...)
Affinity DataIC50:  0.170nMAssay Description:Compound was tested for inhibition against Angiotensin II receptor, type 1More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed