BDBM50067722 CHEMBL3402135

SMILES CN(Cc1ccccc1C)C(=O)CCCN1c2ccccc2N(Cc2ccc(cc2)C(O)(C(F)(F)F)C(F)(F)F)S1(=O)=O

InChI Key InChIKey=YXEDNUNRQAJMBO-UHFFFAOYSA-N

Data  1 IC50  1 Kd

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
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Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 2 hits for monomerid = 50067722   

TargetNuclear receptor ROR-gamma(Human)
Boehringer Ingelheim Pharmaceuticals

Curated by ChEMBL
LigandPNGBDBM50067722(CHEMBL3402135)
Affinity DataIC50: 2.20E+3nMAssay Description:Inverse agonist activity at RORC ligand binding domain (unknown origin) expressed in HEK293 cells transfected with GAL4 promoter by luciferase report...More data for this Ligand-Target Pair
In Depth
Date in BDB:
4/13/2016
Entry Details Article
PubMed
TargetNuclear receptor ROR-gamma(Human)
Boehringer Ingelheim Pharmaceuticals

Curated by ChEMBL
LigandPNGBDBM50067722(CHEMBL3402135)
Affinity DataKd:  2.40E+3nMAssay Description:Binding affinity to RORC-SRC2 fusion construct (unknown origin) by TAMRA-labeled active site probe based fluorescence polarization competition bindin...More data for this Ligand-Target Pair
In Depth
Date in BDB:
4/13/2016
Entry Details Article
PubMed