BDBM50068286 CHEMBL3403373
SMILES CCn1c(NC(C)C)nc2c(csc2c1=O)C1CCN(C1)C(=O)c1ncccc1C
InChI Key InChIKey=JUDJZYCORAYMNM-UHFFFAOYSA-N
Data 4 IC50
Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB
Found 4 hits for monomerid = 50068286
TargetHigh affinity cAMP-specific 3',5'-cyclic phosphodiesterase 7A(Homo sapiens (Human))
Kaken Pharmaceutical
Curated by ChEMBL
Kaken Pharmaceutical
Curated by ChEMBL
Affinity DataIC50: 1.40nMAssay Description:Inhibition of human PDE7A expressed in insect cells assessed as inhibition of [3H]cAMP to [3H]AMP hydrolysis after 30 mins by scintillation countingMore data for this Ligand-Target Pair
TargetcGMP-specific 3',5'-cyclic phosphodiesterase(Homo sapiens (Human))
Kaken Pharmaceutical
Curated by ChEMBL
Kaken Pharmaceutical
Curated by ChEMBL
Affinity DataIC50: 3.10E+3nMAssay Description:Inhibition of PDE5A (unknown origin)More data for this Ligand-Target Pair
TargetcGMP-inhibited 3',5'-cyclic phosphodiesterase 3A(Homo sapiens (Human))
Kaken Pharmaceutical
Curated by ChEMBL
Kaken Pharmaceutical
Curated by ChEMBL
Affinity DataIC50: 1.30E+3nMAssay Description:Inhibition of PDE3A (unknown origin)More data for this Ligand-Target Pair
TargetcAMP-specific 3',5'-cyclic phosphodiesterase 4B(Homo sapiens (Human))
Kaken Pharmaceutical
Curated by ChEMBL
Kaken Pharmaceutical
Curated by ChEMBL
Affinity DataIC50: 140nMAssay Description:Inhibition of human PDE4B expressed in insect cells assessed as inhibition of [3H]cAMP to [3H]AMP hydrolysis after 30 mins by scintillation countingMore data for this Ligand-Target Pair