BDBM50068286 CHEMBL3403373

SMILES CCn1c(NC(C)C)nc2c(csc2c1=O)C1CCN(C1)C(=O)c1ncccc1C

InChI Key InChIKey=JUDJZYCORAYMNM-UHFFFAOYSA-N

Data  4 IC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
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Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 4 hits for monomerid = 50068286   

TargetHigh affinity cAMP-specific 3',5'-cyclic phosphodiesterase 7A(Homo sapiens (Human))
Kaken Pharmaceutical

Curated by ChEMBL
LigandPNGBDBM50068286(CHEMBL3403373)
Affinity DataIC50:  1.40nMAssay Description:Inhibition of human PDE7A expressed in insect cells assessed as inhibition of [3H]cAMP to [3H]AMP hydrolysis after 30 mins by scintillation countingMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetcGMP-specific 3',5'-cyclic phosphodiesterase(Homo sapiens (Human))
Kaken Pharmaceutical

Curated by ChEMBL
LigandPNGBDBM50068286(CHEMBL3403373)
Affinity DataIC50:  3.10E+3nMAssay Description:Inhibition of PDE5A (unknown origin)More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetcGMP-inhibited 3',5'-cyclic phosphodiesterase 3A(Homo sapiens (Human))
Kaken Pharmaceutical

Curated by ChEMBL
LigandPNGBDBM50068286(CHEMBL3403373)
Affinity DataIC50:  1.30E+3nMAssay Description:Inhibition of PDE3A (unknown origin)More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetcAMP-specific 3',5'-cyclic phosphodiesterase 4B(Homo sapiens (Human))
Kaken Pharmaceutical

Curated by ChEMBL
LigandPNGBDBM50068286(CHEMBL3403373)
Affinity DataIC50:  140nMAssay Description:Inhibition of human PDE4B expressed in insect cells assessed as inhibition of [3H]cAMP to [3H]AMP hydrolysis after 30 mins by scintillation countingMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed