BDBM50068702 Biphenyl-2,4'-disulfonic acid 4'-dimethylamide 2-[(3,4-dimethyl-isoxazol-5-yl)-amide]::CHEMBL357099

SMILES CN(C)S(=O)(=O)c1ccc(cc1)-c1ccccc1S(=O)(=O)Nc1onc(C)c1C

InChI Key InChIKey=LFHCHKHNRPXNCK-UHFFFAOYSA-N

Data  2 KI

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
Find this compound or compounds like it in BindingDB:
   Substructure
Similarity at least:  must be >=0.5
Exact match

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 2 hits for monomerid = 50068702   

TargetEndothelin-1 receptor(Rat)
Bristol-Myers Squibb Pharmaceutical Research Institute

Curated by ChEMBL
LigandPNGBDBM50068702(Biphenyl-2,4'-disulfonic acid 4'-dimethylamide 2-[...)
Affinity DataKi:  560nMAssay Description:Ability to inhibit binding of [125I]ET1 to membranes prepared from A10 rat thoracic aorta smooth muscle Endothelin A receptorMore data for this Ligand-Target Pair
In Depth
Date in BDB:
11/9/2012
Entry Details Article
PubMed
TargetEndothelin receptor type B(Rat)
Bristol-Myers Squibb Pharmaceutical Research Institute

Curated by ChEMBL
LigandPNGBDBM50068702(Biphenyl-2,4'-disulfonic acid 4'-dimethylamide 2-[...)
Affinity DataKi: >2.00E+5nMAssay Description:Ability to inhibit binding of [125I]-ET-1 to membranes prepared from A10 rat cerebellum (Endothelin B receptor)More data for this Ligand-Target Pair
In Depth
Date in BDB:
11/9/2012
Entry Details Article
PubMed