BDBM50068775 2H-Isoquinolin-1-one::CHEMBL339695::isoquinolin-1(2H)-one

SMILES: c1ccc2c(c1)C=CNC2=O

InChI Key: InChIKey=VDBNYAPERZTOOF-UHFFFAOYSA-N

Data: 1 KI  3 IC50  1 Kd

PDB links: 2 PDB IDs match this monomer.

Find this compound or compounds like it in BindingDB or PDB:

Substructure Similarity at least:  must be >=0.5 Exact match

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 5 hits for monomerid = 50068775   

Target/Host (Institution)	Ligand	Target/Host Links	Ligand Links	Trg + Lig Links	Ki nM	ΔG° kcal/mole	IC50 nM	Kd nM	EC50 nM	koff s-1	kon M-1s-1	pH	Temp °C
Poly [ADP-ribose] polymerase 1 (Mouse)	BDBM50068775 (isoquinolin-1(2H)-one | 2H-Isoquinolin-1-one | CHE...) Show SMILES Show InChI	GoogleScholar	UniChem		n/a	n/a	1.58E+4	n/a	n/a	n/a	n/a	n/a	n/a
TBA									Citation and Details
					More data for this Ligand-Target Pair
Poly [ADP-ribose] polymerase 1 (Human)	BDBM50068775 (isoquinolin-1(2H)-one | 2H-Isoquinolin-1-one | CHE...) Show SMILES Show InChI	GoogleScholar	UniChem		n/a	n/a	7.00E+3	n/a	n/a	n/a	n/a	n/a	n/a
TBA									Citation and Details
					More data for this Ligand-Target Pair
Poly [ADP-ribose] polymerase 1 (Human)	BDBM50068775 (isoquinolin-1(2H)-one | 2H-Isoquinolin-1-one | CHE...) Show SMILES Show InChI	GoogleScholar	UniChem		n/a	n/a	9	n/a	n/a	n/a	n/a	n/a	n/a
TBA									Citation and Details
					More data for this Ligand-Target Pair
Peregrin (Human)	BDBM50068775 (isoquinolin-1(2H)-one | 2H-Isoquinolin-1-one | CHE...) Show SMILES Show InChI	GoogleScholar	UniChem		n/a	n/a	n/a	>2.00E+5	n/a	n/a	n/a	n/a	n/a
TBA									Citation and Details
					More data for this Ligand-Target Pair
Coagulation factor VII/Tissue factor (Human)	BDBM50068775 (isoquinolin-1(2H)-one | 2H-Isoquinolin-1-one | CHE...) Show SMILES Show InChI	GoogleScholar	UniChem		1.90E+7	n/a	n/a	n/a	n/a	n/a	n/a	n/a	n/a
TBA									Citation and Details
					More data for this Ligand-Target Pair