BDBM50069361 (R)-2-(1-((3-(2-(2-hydroxypropan-2-yl)phenyl)-1-(3-(2-(6-isopropyl-5-methylpyridin-2-yl)vinyl)phenyl)propylthio)methyl)cyclopropyl)acetic acid::CHEMBL344169::[1-((R)-3-[2-(1-Hydroxy-1-methyl-ethyl)-phenyl]-1-{3-[(E)-2-(6-isopropyl-5-methyl-pyridin-2-yl)-vinyl]-phenyl}-propylsulfanylmethyl)-cyclopropyl]-acetic acid

SMILES CC(C)c1nc(\C=C\c2cccc(c2)[C@@H](CCc2ccccc2C(C)(C)O)SCC2(CC(O)=O)CC2)ccc1C

InChI Key InChIKey=BPSQDOLGQQVYNF-NSQLZQESSA-N

Data  3 IC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
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Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 3 hits for monomerid = 50069361   

TargetCysteinyl leukotriene receptor 1/2(Homo sapiens (Human))
Merck Frosst Center For Therapeutic Research

Curated by ChEMBL
LigandPNGBDBM50069361((R)-2-(1-((3-(2-(2-hydroxypropan-2-yl)phenyl)-1-(3...)
Affinity DataIC50:  4.70nMAssay Description:In vitro inhibition of [3H]LTD4 binding to LTD4 receptor of guinea pig lung membrane with human serum albumin (HSA).More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetCysteinyl leukotriene receptor 1(Homo sapiens (Human))
Zhejiang University

Curated by ChEMBL
LigandPNGBDBM50069361((R)-2-(1-((3-(2-(2-hydroxypropan-2-yl)phenyl)-1-(3...)
Affinity DataIC50:  4.90nMAssay Description:Antagonist activity at CysLT1 receptor in human dU937 cells assessed as inhibition of LTD4-induced increase of calcium level treated 30 mins before L...More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetCysteinyl leukotriene receptor 1/2(Homo sapiens (Human))
Merck Frosst Center For Therapeutic Research

Curated by ChEMBL
LigandPNGBDBM50069361((R)-2-(1-((3-(2-(2-hydroxypropan-2-yl)phenyl)-1-(3...)
Affinity DataIC50:  4.90nMAssay Description:In vitro inhibition of [3H]-LTD4 binding to LTD4 receptor of guinea pig lung membrane without human serum albumin (HSA).More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed