BDBM50069373 2-(1-(((1R)-3-(2-(2-hydroxypropan-2-yl)phenyl)-1-(3-((E)-2-(8-methyl-5,6,7,8-tetrahydroquinolin-2-yl)vinyl)phenyl)propylthio)methyl)cyclopropyl)acetic acid::CHEMBL342705::[1-((R)-3-[2-(1-Hydroxy-1-methyl-ethyl)-phenyl]-1-{3-[(E)-2-(8-methyl-5,6,7,8-tetrahydro-quinolin-2-yl)-vinyl]-phenyl}-propylsulfanylmethyl)-cyclopropyl]-acetic acid
SMILES CC1CCCc2ccc(\C=C\c3cccc(c3)[C@@H](CCc3ccccc3C(C)(C)O)SCC3(CC(O)=O)CC3)nc12
InChI Key InChIKey=DUCNKECWDRIBHL-YCYFMJLASA-N
Data 4 IC50
Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB
Found 4 hits for monomerid = 50069373
TargetCysteinyl leukotriene receptor 1(Homo sapiens (Human))
Merck Frosst Center For Therapeutic Research
Curated by ChEMBL
Merck Frosst Center For Therapeutic Research
Curated by ChEMBL
Affinity DataIC50: 0.470nMAssay Description:In vitro inhibition of [3H]-LTD4 binding to LTD4 receptor of DMSO differentiated human U937 cell membranesMore data for this Ligand-Target Pair
TargetCysteinyl leukotriene receptor 1(Homo sapiens (Human))
Merck Frosst Center For Therapeutic Research
Curated by ChEMBL
Merck Frosst Center For Therapeutic Research
Curated by ChEMBL
Affinity DataIC50: 0.510nMAssay Description:Antagonist activity at CysLT1 receptor in human dU937 cells assessed as inhibition of LTD4-induced increase of calcium level treated 30 mins before L...More data for this Ligand-Target Pair
TargetCysteinyl leukotriene receptor 1/2(Homo sapiens (Human))
Merck Frosst Center For Therapeutic Research
Curated by ChEMBL
Merck Frosst Center For Therapeutic Research
Curated by ChEMBL
Affinity DataIC50: 0.630nMAssay Description:In vitro inhibition of [3H]LTD4 binding to LTD4 receptor of guinea pig lung membrane with human serum albumin (HSA).More data for this Ligand-Target Pair
TargetCysteinyl leukotriene receptor 1/2(Homo sapiens (Human))
Merck Frosst Center For Therapeutic Research
Curated by ChEMBL
Merck Frosst Center For Therapeutic Research
Curated by ChEMBL
Affinity DataIC50: 0.510nMAssay Description:In vitro inhibition of [3H]-LTD4 binding to LTD4 receptor of guinea pig lung membrane without human serum albumin (HSA).More data for this Ligand-Target Pair