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BDBM50069423 4-(4-{3-[2-(4-Chloro-phenoxymethyl)-4-methyl-benzoimidazol-1-yl]-propyl}-piperidin-1-yl)-1-piperidin-1-yl-butan-1-one::CHEMBL145396

SMILES: Cc1cccc2n(CCCC3CCN(CCCC(=O)N4CCCCC4)CC3)c(COc3ccc(Cl)cc3)nc12

InChI Key: InChIKey=UDFQNKWLOCRQMR-UHFFFAOYSA-N

Data: 1 KI

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Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 1 hit for monomerid = 50069423   
Target/Host
(Institution)
LigandTarget/Host
Links
Ligand
Links
Trg + Lig
Links
Ki
nM
ΔG°
kcal/mole
IC50
nM
Kd
nM
EC50/IC50
nM
koff
s-1
kon
M-1s-1
pHTemp
°C
Neuropeptide Y receptor type 1


(Homo sapiens (Human))
BDBM50069423
PNG
(4-(4-{3-[2-(4-Chloro-phenoxymethyl)-4-methyl-benzo...)
Show SMILES Cc1cccc2n(CCCC3CCN(CCCC(=O)N4CCCCC4)CC3)c(COc3ccc(Cl)cc3)nc12
Show InChI InChI=1S/C32H43ClN4O2/c1-25-8-5-10-29-32(25)34-30(24-39-28-14-12-27(33)13-15-28)37(29)21-6-9-26-16-22-35(23-17-26)18-7-11-31(38)36-19-3-2-4-20-36/h5,8,10,12-15,26H,2-4,6-7,9,11,16-24H2,1H3
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Similars

Article
PubMed
21n/an/an/an/an/an/an/an/a



Eli Lilly and Company

Curated by ChEMBL


Assay Description
Binding affinity at cloned Neuropeptide Y-1 receptor expressed in AV-12 cells is evaluated.


Bioorg Med Chem Lett 8: 473-6 (1999)


Article DOI: 10.1016/s0960-894x(98)00048-1
BindingDB Entry DOI: 10.7270/Q2GH9H33
More data for this
Ligand-Target Pair