BDBM50069440 CHEMBL3403612

SMILES [#8]-[#6](=O)-[#6]-1-[#6]-[#7]-[#6]-[#6]-[#7](-[#6]-[#6]-[#8]\[#7]=[#6](\c2ccccc2)-c2ccccc2)-[#6]-1

InChI Key InChIKey=NGRLJVLUQWCBOW-UHFFFAOYSA-N

Data  5 IC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
Find this compound or compounds like it in BindingDB:
   Substructure
Similarity at least:  must be >=0.5
Exact match

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 5 hits for monomerid = 50069440   

TargetSodium- and chloride-dependent GABA transporter 1(Rat)
University of Copenhagen

Curated by ChEMBL
LigandPNGBDBM50069440(CHEMBL3403612)
Affinity DataIC50: 6.67E+5nMAssay Description:Inhibition of mouse mGAT1 expressed in HEK293 cells assessed as inhibition of [3H]GABA uptake after 3 mins incubation by TopCount microplate scintill...More data for this Ligand-Target Pair
In Depth
Date in BDB:
4/14/2016
Entry Details Article
PubMed
TargetSodium- and chloride-dependent GABA transporter 1(Rat)
University of Copenhagen

Curated by ChEMBL
LigandPNGBDBM50069440(CHEMBL3403612)
Affinity DataIC50: 6.67E+5nMAssay Description:Inhibition of mouse mGAT1 expressed in HEK293 cells assessed as inhibition of [3H]GABA uptake after 3 mins incubation by TopCount microplate scintill...More data for this Ligand-Target Pair
In Depth
Date in BDB:
4/14/2016
Entry Details Article
PubMed
TargetSodium- and chloride-dependent betaine transporter(Mouse)
University of Copenhagen

Curated by ChEMBL
LigandPNGBDBM50069440(CHEMBL3403612)
Affinity DataIC50: 1.00E+6nMAssay Description:Inhibition of mouse mGAT2 expressed in HEK293 cells assessed as inhibition of [3H]GABA uptake after 3 mins incubation by TopCount microplate scintill...More data for this Ligand-Target Pair
In Depth
Date in BDB:
4/14/2016
Entry Details Article
PubMed
TargetSodium- and chloride-dependent GABA transporter 2(Mouse)
University of Copenhagen

Curated by ChEMBL
LigandPNGBDBM50069440(CHEMBL3403612)
Affinity DataIC50: 1.00E+6nMAssay Description:Inhibition of mouse mGAT3 expressed in HEK293 cells assessed as inhibition of [3H]GABA uptake after 3 mins incubation by TopCount microplate scintill...More data for this Ligand-Target Pair
In Depth
Date in BDB:
4/14/2016
Entry Details Article
PubMed
TargetSodium- and chloride-dependent GABA transporter 3(Mouse)
University of Copenhagen

Curated by ChEMBL
LigandPNGBDBM50069440(CHEMBL3403612)
Affinity DataIC50: 1.00E+6nMAssay Description:Inhibition of mouse mGAT4 expressed in HEK293 cells assessed as inhibition of [3H]GABA uptake after 3 mins incubation by TopCount microplate scintill...More data for this Ligand-Target Pair
In Depth
Date in BDB:
4/14/2016
Entry Details Article
PubMed