BDBM50069595 (2R,3S)-2-Benzyl-N*1*-((S)-1-carbamoyl-2-phenyl-ethyl)-N*4*-hydroxy-3-(thiophen-2-ylsulfanylmethyl)-succinamide::CHEMBL113764

SMILES NC(=O)[C@H](Cc1ccccc1)NC(=O)[C@H](Cc1ccccc1)[C@H](CSc1cccs1)C(=O)NO

InChI Key InChIKey=UJLOAPKMIFCFBZ-UHFFFAOYSA-N

Data  2 IC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
Find this compound or compounds like it in BindingDB:
   Substructure
Similarity at least:  must be >=0.5
Exact match

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 2 hits for monomerid = 50069595   

TargetLow affinity immunoglobulin epsilon Fc receptor(Human)
Smithkline Beecham Pharmaceuticals

Curated by ChEMBL
LigandPNGBDBM50069595((2R,3S)-2-Benzyl-N*1*-((S)-1-carbamoyl-2-phenyl-et...)
Affinity DataIC50: 160nMAssay Description:Tested for inhibition against CD23 (IgE receptor) proteolysis in membranes derived from RPM18866 cells ( a human B-cell line); value ranges from 100-...More data for this Ligand-Target Pair
In Depth
Date in BDB:
11/10/2009
Entry Details Article
PubMed
TargetInterstitial collagenase(Human)
Smithkline Beecham Pharmaceuticals

Curated by ChEMBL
LigandPNGBDBM50069595((2R,3S)-2-Benzyl-N*1*-((S)-1-carbamoyl-2-phenyl-et...)
Affinity DataIC50: 930nMAssay Description:Inhibitory activity towards human recombinant fibroblast collagenaseMore data for this Ligand-Target Pair
In Depth
Date in BDB:
11/10/2009
Entry Details Article
PubMed