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BDBM50069947 CHEMBL441276::Sodium; 9-fluoro-3-(4-methoxy-phenyl)-5,6-dihydro-benzo[c]acridine-7-carboxylate

SMILES: COc1ccc(cc1)-c1ccc-2c(CCc3c-2nc2ccc(F)cc2c3C([O-])=O)c1

InChI Key: InChIKey=FCEQSNMCOTWBRL-UHFFFAOYSA-M

Data: 1 KI

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Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 1 hit for monomerid = 50069947   
Target/Host
(Institution)
LigandTarget/Host
Links
Ligand
Links
Trg + Lig
Links
Ki
nM
ΔG°
kcal/mole
IC50
nM
Kd
nM
EC50/IC50
nM
koff
s-1
kon
M-1s-1
pHTemp
°C
Dihydroorotate dehydrogenase


(Homo sapiens (Human))
BDBM50069947
PNG
(CHEMBL441276 | Sodium; 9-fluoro-3-(4-methoxy-pheny...)
Show SMILES COc1ccc(cc1)-c1ccc-2c(CCc3c-2nc2ccc(F)cc2c3C([O-])=O)c1
Show InChI InChI=1S/C25H18FNO3/c1-30-18-7-2-14(3-8-18)15-4-9-19-16(12-15)5-10-20-23(25(28)29)21-13-17(26)6-11-22(21)27-24(19)20/h2-4,6-9,11-13H,5,10H2,1H3,(H,28,29)/p-1
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Similars

Article
PubMed
55n/an/an/an/an/an/an/an/a



DuPont Pharmaceuticals Company

Curated by ChEMBL


Assay Description
Inhibition of human recombinant dihydroorotate dehydrogenase (DHODase)


Bioorg Med Chem Lett 8: 307-12 (1999)


Article DOI: 10.1016/s0960-894x(98)00010-9
BindingDB Entry DOI: 10.7270/Q21C1W19
More data for this
Ligand-Target Pair