BDBM50070181 1-(3-Dimethylamino-propyl)-3-ethyl-1-((6aR,9R,10aR)-7-methyl-4,6,6a,7,8,9,10,10a-octahydro-indolo[4,3-fg]quinoline-9-carbonyl)-urea::CHEMBL14022
SMILES CCNC(=O)N(CCCN(C)C)C(=O)[C@@H]1C[C@H]2[C@@H](Cc3c[nH]c4cccc2c34)N(C)C1
InChI Key InChIKey=XEMCUJCVRDSIHH-YFVAEKQCSA-N
Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB
Found 8 hits for monomerid = 50070181
Affinity DataKi: 2.20nMAssay Description:Displacement of [125I](+/-)DOI from human 5-HT2B receptor trasfected in CHO cell membrane after 60 mins by scintillation counting analysisMore data for this Ligand-Target Pair
Affinity DataIC50: 310nMAssay Description:Displacement of [3H]-8-OH-DPAT from 5-hydroxytryptamine 1A receptor in rat hippocampusMore data for this Ligand-Target Pair
Affinity DataIC50: 50nMAssay Description:Displacement of [3H]-spiroperidol from D2 receptor in rat striatumMore data for this Ligand-Target Pair
TargetAlpha-2A adrenergic receptor [16-465]/Alpha-2B adrenergic receptor/Alpha-2C adrenergic receptor(RAT)
Pharmacia & Upjohn
Curated by ChEMBL
Pharmacia & Upjohn
Curated by ChEMBL
Affinity DataIC50: 1.27E+3nMAssay Description:Displacement of [3H]yohimbine from Alpha-2 adrenergic receptor in rat frontal cortexMore data for this Ligand-Target Pair
TargetAlpha-1A/Alpha-1B/Alpha-1D adrenergic receptor(Rattus norvegicus (rat))
Pharmacia & Upjohn
Curated by ChEMBL
Pharmacia & Upjohn
Curated by ChEMBL
Affinity DataIC50: 2.55E+3nMAssay Description:Displacement of [3H]prazosin from Alpha-1 adrenergic receptor in rat frontal cortexMore data for this Ligand-Target Pair
Affinity DataIC50: 280nMAssay Description:Displacement of [3H]ketanserin from 5-hydroxytryptamine 2 receptor in rat pre frontal cortexMore data for this Ligand-Target Pair
Affinity DataIC50: 850nMAssay Description:Displacement of [3H]-SCH-23,390 from D1 receptor in rat striatumMore data for this Ligand-Target Pair
Affinity DataEC50: 16nMAssay Description:Agonist activity at human 5-HT2B receptor transfected in CHO cell assessed as IP1 production incubated for 30 mins measured by HTRF detection methodMore data for this Ligand-Target Pair