BDBM50070183 (6aR,9R,10aR)-2-tert-Butyl-7,9-dimethyl-4,6,6a,7,8,9,10,10a-octahydro-indolo[4,3-fg]quinoline::CHEMBL14138

SMILES C[C@@H]1C[C@H]2[C@@H](Cc3c[nH]c4cc(cc2c34)C(C)(C)C)N(C)C1

InChI Key InChIKey=FLTZEKITQLGBQU-CDHAZOANSA-N

Data  6 IC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
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Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 6 hits for monomerid = 50070183   

TargetD(2) dopamine receptor(Rattus norvegicus (rat))
Pharmacia & Upjohn

Curated by ChEMBL
LigandPNGBDBM50070183((6aR,9R,10aR)-2-tert-Butyl-7,9-dimethyl-4,6,6a,7,8...)
Affinity DataIC50:  9.13E+3nMAssay Description:Displacement of [3H]-spiroperidol from D2 receptor in rat striatumMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
Target5-hydroxytryptamine receptor 1A(Rattus norvegicus (rat))
Pharmacia & Upjohn

Curated by ChEMBL
LigandPNGBDBM50070183((6aR,9R,10aR)-2-tert-Butyl-7,9-dimethyl-4,6,6a,7,8...)
Affinity DataIC50:  230nMAssay Description:Displacement of [3H]-8-OH-DPAT from 5-hydroxytryptamine 1A receptor in rat hippocampusMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetAlpha-1A/Alpha-1B/Alpha-1D adrenergic receptor(Rattus norvegicus (rat))
Pharmacia & Upjohn

Curated by ChEMBL
LigandPNGBDBM50070183((6aR,9R,10aR)-2-tert-Butyl-7,9-dimethyl-4,6,6a,7,8...)
Affinity DataIC50:  8.95E+3nMAssay Description:Displacement of [3H]prazosin from Alpha-1 adrenergic receptor in rat frontal cortexMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetSerotonin 2 (5-HT2) receptor(RAT)
Pharmacia & Upjohn

Curated by ChEMBL
LigandPNGBDBM50070183((6aR,9R,10aR)-2-tert-Butyl-7,9-dimethyl-4,6,6a,7,8...)
Affinity DataIC50:  4.94E+3nMAssay Description:Displacement of [3H]ketanserin from 5-hydroxytryptamine 2 receptor in rat pre frontal cortexMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
LigandPNGBDBM50070183((6aR,9R,10aR)-2-tert-Butyl-7,9-dimethyl-4,6,6a,7,8...)
Affinity DataIC50:  1.76E+3nMAssay Description:Displacement of [3H]yohimbine from Alpha-2 adrenergic receptor in rat frontal cortexMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetD(1A) dopamine receptor(RAT)
Pharmacia & Upjohn

Curated by ChEMBL
LigandPNGBDBM50070183((6aR,9R,10aR)-2-tert-Butyl-7,9-dimethyl-4,6,6a,7,8...)
Affinity DataIC50: >1.00E+4nMAssay Description:Displacement of [3H]-SCH-23,390 from D1 receptor in rat striatumMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed