BDBM50070202 CHEMBL267799::N-((6aR,9S,10aR)-3-tert-Butyl-7-methyl-4,6,6a,7,8,9,10,10a-octahydro-indolo[4,3-fg]quinolin-9-ylmethyl)-benzamide

SMILES CN1C[C@H](CNC(=O)c2ccccc2)C[C@H]2[C@H]1Cc1c[nH]c3c(ccc2c13)C(C)(C)C

InChI Key InChIKey=MOWAUISIARUDCJ-AMHTUMDSSA-N

Data  6 IC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
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Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 6 hits for monomerid = 50070202   

TargetD(2) dopamine receptor(Rattus norvegicus (rat))
Pharmacia & Upjohn

Curated by ChEMBL
LigandPNGBDBM50070202(CHEMBL267799 | N-((6aR,9S,10aR)-3-tert-Butyl-7-met...)
Affinity DataIC50:  2.07E+3nMAssay Description:Displacement of [3H]-spiroperidol from D2 receptor in rat striatumMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetD(1A) dopamine receptor(RAT)
Pharmacia & Upjohn

Curated by ChEMBL
LigandPNGBDBM50070202(CHEMBL267799 | N-((6aR,9S,10aR)-3-tert-Butyl-7-met...)
Affinity DataIC50: >1.00E+4nMAssay Description:Displacement of [3H]-SCH-23,390 from D1 receptor in rat striatumMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetAlpha-1A/Alpha-1B/Alpha-1D adrenergic receptor(Rattus norvegicus (rat))
Pharmacia & Upjohn

Curated by ChEMBL
LigandPNGBDBM50070202(CHEMBL267799 | N-((6aR,9S,10aR)-3-tert-Butyl-7-met...)
Affinity DataIC50: >1.00E+4nMAssay Description:Displacement of [3H]prazosin from Alpha-1 adrenergic receptor in rat frontal cortexMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetSerotonin 2 (5-HT2) receptor(RAT)
Pharmacia & Upjohn

Curated by ChEMBL
LigandPNGBDBM50070202(CHEMBL267799 | N-((6aR,9S,10aR)-3-tert-Butyl-7-met...)
Affinity DataIC50:  48nMAssay Description:Displacement of [3H]ketanserin from 5-hydroxytryptamine 2 receptor in rat pre frontal cortexMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
LigandPNGBDBM50070202(CHEMBL267799 | N-((6aR,9S,10aR)-3-tert-Butyl-7-met...)
Affinity DataIC50:  710nMAssay Description:Displacement of [3H]yohimbine from Alpha-2 adrenergic receptor in rat frontal cortexMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
Target5-hydroxytryptamine receptor 1A(Rattus norvegicus (rat))
Pharmacia & Upjohn

Curated by ChEMBL
LigandPNGBDBM50070202(CHEMBL267799 | N-((6aR,9S,10aR)-3-tert-Butyl-7-met...)
Affinity DataIC50:  31nMAssay Description:Displacement of [3H]-8-OH-DPAT from 5-hydroxytryptamine 1A receptor in rat hippocampusMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed