BDBM50070435 2-Oxo-4-(pyridin-2-ylmethylsulfanyl)-azetidine-1-carboxylic acid ((R)-1-phenyl-propyl)-amide::CHEMBL35797

SMILES CC[C@@H](NC(=O)N1C(CC1=O)SCc1ccccn1)c1ccccc1

InChI Key InChIKey=HOPRIRGXAOEBRS-PYUWXLGESA-N

Data  5 IC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
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   Substructure
Similarity at least:  must be >=0.5
Exact match

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 5 hits for monomerid = 50070435   

TargetCapsid scaffolding protein(Human cytomegalovirus (strain AD169) (HHV-5) (Huma...)
Boehringer Ingelheim (Canada)

Curated by ChEMBL
LigandPNGBDBM50070435(2-Oxo-4-(pyridin-2-ylmethylsulfanyl)-azetidine-1-c...)
Affinity DataIC50:  1.20E+3nMAssay Description:Inhibitory activity against human cytomegalovirus(HCMV) proteaseMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetCathepsin B(Homo sapiens (Human))
Boehringer Ingelheim (Canada)

Curated by ChEMBL
LigandPNGBDBM50070435(2-Oxo-4-(pyridin-2-ylmethylsulfanyl)-azetidine-1-c...)
Affinity DataIC50: >7.50E+4nMAssay Description:Inhibitory activity against Cathepsin BMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetChymotrypsinogen B(Homo sapiens (Human))
Boehringer Ingelheim (Canada)

Curated by ChEMBL
LigandPNGBDBM50070435(2-Oxo-4-(pyridin-2-ylmethylsulfanyl)-azetidine-1-c...)
Affinity DataIC50: >7.50E+4nMAssay Description:Inhibitory activity against alpha-chymotrypsinMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetNeutrophil elastase(Homo sapiens (Human))
Boehringer Ingelheim (Canada)

Curated by ChEMBL
LigandPNGBDBM50070435(2-Oxo-4-(pyridin-2-ylmethylsulfanyl)-azetidine-1-c...)
Affinity DataIC50: >7.50E+4nMAssay Description:Inhibitory activity against human leukocyte elastase protease(HLE)More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetChymotrypsin-like elastase family member 2A(Sus scrofa)
Boehringer Ingelheim (Canada)

Curated by ChEMBL
LigandPNGBDBM50070435(2-Oxo-4-(pyridin-2-ylmethylsulfanyl)-azetidine-1-c...)
Affinity DataIC50:  2.30E+4nMAssay Description:Inhibitory activity against porcine pancreatic elastase(PPE)More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed