BDBM50070440 CHEMBL35762::{(S)-1-[(S)-1-(1-Benzylcarbamoyl-4-oxo-azetidin-2-ylsulfanylmethyl)-3-methyl-butylcarbamoyl]-2,2-dimethyl-propyl}-carbamic acid tert-butyl ester

SMILES CC(C)C[C@@H](CSC1CC(=O)N1C(=O)NCc1ccccc1)NC(=O)[C@@H](NC(=O)OC(C)(C)C)C(C)(C)C

InChI Key InChIKey=UEAVISVLNUMJDB-XLSWHLDHSA-N

Data  5 IC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
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Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 5 hits for monomerid = 50070440   

TargetChymotrypsin-like elastase family member 2A(Sus scrofa)
Boehringer Ingelheim (Canada)

Curated by ChEMBL
LigandPNGBDBM50070440(CHEMBL35762 | {(S)-1-[(S)-1-(1-Benzylcarbamoyl-4-o...)
Affinity DataIC50: >7.50E+4nMAssay Description:Inhibitory activity against porcine pancreatic elastase(PPE)More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetNeutrophil elastase(Homo sapiens (Human))
Boehringer Ingelheim (Canada)

Curated by ChEMBL
LigandPNGBDBM50070440(CHEMBL35762 | {(S)-1-[(S)-1-(1-Benzylcarbamoyl-4-o...)
Affinity DataIC50: >7.50E+4nMAssay Description:Inhibitory activity against human leukocyte elastase protease(HLE)More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetChymotrypsinogen B(Homo sapiens (Human))
Boehringer Ingelheim (Canada)

Curated by ChEMBL
LigandPNGBDBM50070440(CHEMBL35762 | {(S)-1-[(S)-1-(1-Benzylcarbamoyl-4-o...)
Affinity DataIC50:  800nMAssay Description:Inhibitory activity against alpha-chymotrypsinMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetCathepsin B(Homo sapiens (Human))
Boehringer Ingelheim (Canada)

Curated by ChEMBL
LigandPNGBDBM50070440(CHEMBL35762 | {(S)-1-[(S)-1-(1-Benzylcarbamoyl-4-o...)
Affinity DataIC50: >7.50E+4nMAssay Description:Inhibitory activity against Cathepsin BMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetCapsid scaffolding protein(Human cytomegalovirus (strain AD169) (HHV-5) (Huma...)
Boehringer Ingelheim (Canada)

Curated by ChEMBL
LigandPNGBDBM50070440(CHEMBL35762 | {(S)-1-[(S)-1-(1-Benzylcarbamoyl-4-o...)
Affinity DataIC50:  400nMAssay Description:Inhibitory activity against human cytomegalovirus(HCMV) proteaseMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed