BDBM50070444 (3R,4S)-3-Methyl-2-oxo-4-(pyridin-2-ylmethylsulfanyl)-azetidine-1-carboxylic acid ((R)-1-phenyl-propyl)-amide::CHEMBL34840

SMILES CC[C@@H](NC(=O)N1[C@@H](SCc2ccccn2)[C@H](C)C1=O)c1ccccc1

InChI Key InChIKey=YJXLFWWMHXAZHE-BJZITVGISA-N

Data  4 IC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
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Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 4 hits for monomerid = 50070444   

TargetCathepsin B(Homo sapiens (Human))
Boehringer Ingelheim (Canada)

Curated by ChEMBL
LigandPNGBDBM50070444((3R,4S)-3-Methyl-2-oxo-4-(pyridin-2-ylmethylsulfan...)
Affinity DataIC50: >7.50E+4nMAssay Description:Inhibitory activity against Cathepsin BMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetNeutrophil elastase(Homo sapiens (Human))
Boehringer Ingelheim (Canada)

Curated by ChEMBL
LigandPNGBDBM50070444((3R,4S)-3-Methyl-2-oxo-4-(pyridin-2-ylmethylsulfan...)
Affinity DataIC50: <150nMAssay Description:Inhibitory activity against alpha-chymotrypsinMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetChymotrypsinogen B(Homo sapiens (Human))
Boehringer Ingelheim (Canada)

Curated by ChEMBL
LigandPNGBDBM50070444((3R,4S)-3-Methyl-2-oxo-4-(pyridin-2-ylmethylsulfan...)
Affinity DataIC50:  1.70E+3nMAssay Description:Inhibitory activity against alpha-chymotrypsinMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetChymotrypsin-like elastase family member 2A(Sus scrofa)
Boehringer Ingelheim (Canada)

Curated by ChEMBL
LigandPNGBDBM50070444((3R,4S)-3-Methyl-2-oxo-4-(pyridin-2-ylmethylsulfan...)
Affinity DataIC50:  730nMAssay Description:Inhibitory activity against porcine pancreatic elastase(PPE)More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed