BDBM50070446 ((S)-2,2-Dimethyl-1-{(S)-3-methyl-1-[4-oxo-1-((S)-1-phenyl-ethylcarbamoyl)-azetidin-2-yloxymethyl]-butylcarbamoyl}-propyl)-carbamic acid tert-butyl ester::CHEMBL32166

SMILES CC(C)C[C@@H](COC1CC(=O)N1C(=O)N[C@@H](C)c1ccccc1)NC(=O)[C@@H](NC(=O)OC(C)(C)C)C(C)(C)C

InChI Key InChIKey=YHXLZLPAZVBADQ-BHDTVSORSA-N

Data  5 IC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
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Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 5 hits for monomerid = 50070446   

TargetNeutrophil elastase(Homo sapiens (Human))
Boehringer Ingelheim (Canada)

Curated by ChEMBL
LigandPNGBDBM50070446(((S)-2,2-Dimethyl-1-{(S)-3-methyl-1-[4-oxo-1-((S)-...)
Affinity DataIC50: >7.50E+4nMAssay Description:Inhibitory activity against human leukocyte elastase protease(HLE)More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetCapsid scaffolding protein(Human cytomegalovirus (strain AD169) (HHV-5) (Huma...)
Boehringer Ingelheim (Canada)

Curated by ChEMBL
LigandPNGBDBM50070446(((S)-2,2-Dimethyl-1-{(S)-3-methyl-1-[4-oxo-1-((S)-...)
Affinity DataIC50:  300nMAssay Description:Inhibitory activity against human cytomegalovirus(HCMV) proteaseMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetChymotrypsinogen B(Homo sapiens (Human))
Boehringer Ingelheim (Canada)

Curated by ChEMBL
LigandPNGBDBM50070446(((S)-2,2-Dimethyl-1-{(S)-3-methyl-1-[4-oxo-1-((S)-...)
Affinity DataIC50: >7.50E+4nMAssay Description:Inhibitory activity against alpha-chymotrypsinMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetCathepsin B(Homo sapiens (Human))
Boehringer Ingelheim (Canada)

Curated by ChEMBL
LigandPNGBDBM50070446(((S)-2,2-Dimethyl-1-{(S)-3-methyl-1-[4-oxo-1-((S)-...)
Affinity DataIC50: >7.50E+4nMAssay Description:Inhibitory activity against Cathepsin BMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetChymotrypsin-like elastase family member 2A(Sus scrofa)
Boehringer Ingelheim (Canada)

Curated by ChEMBL
LigandPNGBDBM50070446(((S)-2,2-Dimethyl-1-{(S)-3-methyl-1-[4-oxo-1-((S)-...)
Affinity DataIC50: >7.50E+4nMAssay Description:Inhibitory activity against porcine pancreatic elastase(PPE)More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed