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BDBM50070507 CHEMBL3408807

SMILES: Nc1ncnc2c3cc(cnc3sc12)-c1ccc2OCOc2c1

InChI Key: InChIKey=XRBJGODILDBFFI-UHFFFAOYSA-N

Data: 2 IC50

Find this compound or compounds like it in BindingDB or PDB:
   Substructure
Similarity at least:  must be >=0.5
Exact match

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 2 hits for monomerid = 50070507   
Target/Host
(Institution)
LigandTarget/Host
Links
Ligand
Links
Trg + Lig
Links
Ki
nM
ΔG°
kcal/mole
IC50
nM
Kd
nM
EC50/IC50
nM
koff
s-1
kon
M-1s-1
pHTemp
°C
Dual specificty protein kinase CLK1


(Homo sapiens (Human))
BDBM50070507
PNG
(CHEMBL3408807)
Show SMILES Nc1ncnc2c3cc(cnc3sc12)-c1ccc2OCOc2c1
Show InChI InChI=1S/C16H10N4O2S/c17-15-14-13(19-6-20-15)10-3-9(5-18-16(10)23-14)8-1-2-11-12(4-8)22-7-21-11/h1-6H,7H2,(H2,17,19,20)
PDB
MMDB

KEGG

UniProtKB/SwissProt

B.MOAD
antibodypedia
GoogleScholar
CHEMBL
PC cid
PC sid
UniChem

Similars

Article
PubMed
n/an/a 520n/an/an/an/an/an/a



COBRA

Curated by ChEMBL


Assay Description
Inhibition of human recombinant GST-tagged CLK1 expressed in Escherichia coli using GRSRSRSRSRSR as substrate after 30 mins


Eur J Med Chem 92: 124-34 (2015)


Article DOI: 10.1016/j.ejmech.2014.12.038
BindingDB Entry DOI: 10.7270/Q2BR8TVG
More data for this
Ligand-Target Pair
Dual-specificity tyrosine-(Y)-phosphorylation regulated kinase 1A


(RAT)
BDBM50070507
PNG
(CHEMBL3408807)
Show SMILES Nc1ncnc2c3cc(cnc3sc12)-c1ccc2OCOc2c1
Show InChI InChI=1S/C16H10N4O2S/c17-15-14-13(19-6-20-15)10-3-9(5-18-16(10)23-14)8-1-2-11-12(4-8)22-7-21-11/h1-6H,7H2,(H2,17,19,20)
PDB

Reactome pathway

UniProtKB/SwissProt

GoogleScholar
CHEMBL
PC cid
PC sid
UniChem

Similars

Article
PubMed
n/an/a 3.80E+3n/an/an/an/an/an/a



COBRA

Curated by ChEMBL


Assay Description
Inhibition of rat recombinant GST-tagged DYRK1A expressed in Escherichia coli using KKISGRLSPIMTEQ as substrate after 30 mins by scintillation counti...


Eur J Med Chem 92: 124-34 (2015)


Article DOI: 10.1016/j.ejmech.2014.12.038
BindingDB Entry DOI: 10.7270/Q2BR8TVG
More data for this
Ligand-Target Pair