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BDBM50070604 CHEMBL3408984

SMILES: CCCCn1c2CCNCc2c2cc(ccc12)-c1cnc(N)nc1

InChI Key: InChIKey=BYLXYXCBEUNQOO-UHFFFAOYSA-N

Data: 1 IC50

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   Substructure
Similarity at least:  must be >=0.5
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Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 1 hit for monomerid = 50070604   
Target/Host
(Institution)
LigandTarget/Host
Links
Ligand
Links
Trg + Lig
Links
Ki
nM
ΔG°
kcal/mole
IC50
nM
Kd
nM
EC50/IC50
nM
koff
s-1
kon
M-1s-1
pHTemp
°C
NAD-dependent deacetylase sirtuin 2


(Homo sapiens (Human))
BDBM50070604
PNG
(CHEMBL3408984)
Show SMILES CCCCn1c2CCNCc2c2cc(ccc12)-c1cnc(N)nc1
Show InChI InChI=1S/C19H23N5/c1-2-3-8-24-17-5-4-13(14-10-22-19(20)23-11-14)9-15(17)16-12-21-7-6-18(16)24/h4-5,9-11,21H,2-3,6-8,12H2,1H3,(H2,20,22,23)
PDB
MMDB

NCI pathway
KEGG

UniProtKB/SwissProt

B.MOAD
GoogleScholar
CHEMBL
PC cid
PC sid
UniChem

Similars

Article
PubMed
n/an/a>1.00E+5n/an/an/an/an/an/a



National University of Singapore

Curated by ChEMBL


Assay Description
Inhibition of human recombinant SIRT2 assessed as deacetylation of N-acetyl lysine residue in p53 (317 to 320) after 30 mins by luciferase-mediated l...


Eur J Med Chem 92: 145-55 (2015)


Article DOI: 10.1016/j.ejmech.2014.12.027
BindingDB Entry DOI: 10.7270/Q270834V
More data for this
Ligand-Target Pair