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BDBM50071119 CHEMBL56143::N-{2-(3,4-Dichloro-phenyl)-4-[4-(1-hydroxy-1-propyl-butyl)-piperidin-1-yl]-butyl}-N-methyl-benzamide

SMILES: CCCC(O)(CCC)C1CCN(CCC(CN(C)C(=O)c2ccccc2)c2ccc(Cl)c(Cl)c2)CC1

InChI Key: InChIKey=VQBKCXBPQSWWAZ-UHFFFAOYNA-N

Data: 1 KI

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Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 1 hit for monomerid = 50071119   
Target/Host
(Institution)
LigandTarget/Host
Links
Ligand
Links
Trg + Lig
Links
Ki
nM
ΔG°
kcal/mole
IC50
nM
Kd
nM
EC50/IC50
nM
koff
s-1
kon
M-1s-1
pHTemp
°C
Substance-K receptor


(Homo sapiens (Human))
BDBM50071119
PNG
(CHEMBL56143 | N-{2-(3,4-Dichloro-phenyl)-4-[4-(1-h...)
Show SMILES CCCC(O)(CCC)C1CCN(CCC(CN(C)C(=O)c2ccccc2)c2ccc(Cl)c(Cl)c2)CC1
Show InChI InChI=1/C30H42Cl2N2O2/c1-4-16-30(36,17-5-2)26-14-19-34(20-15-26)18-13-25(24-11-12-27(31)28(32)21-24)22-33(3)29(35)23-9-7-6-8-10-23/h6-12,21,25-26,36H,4-5,13-20,22H2,1-3H3
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PC sid
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Similars

Article
PubMed
4.70n/an/an/an/an/an/an/an/a



Zeneca Pharmaceuticals

Curated by ChEMBL


Assay Description
Displacement of [3H]- NKA from human NK-2 receptor expressed in MEL cells


Bioorg Med Chem Lett 8: 1935-40 (1999)


Article DOI: 10.1016/s0960-894x(98)00037-7
BindingDB Entry DOI: 10.7270/Q2J38RPQ
More data for this
Ligand-Target Pair