BDBM50071174 2-Methyl-9-phenoxy-11,12-dihydro-3H,6aH,13H-6-oxa-3,12a-diaza-benzo[a]cyclopenta[h]anthracene-1-carboxylic acid ethyl ester::CHEMBL61700

SMILES CCOC(=O)c1c(C)[nH]c2ccc3OC4N(CCc5cc(Oc6ccccc6)ccc45)Cc3c12

InChI Key InChIKey=QELYJMWPIJVOGA-UHFFFAOYSA-N

Data  5 IC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
Find this compound or compounds like it in BindingDB:
   Substructure
Similarity at least:  must be >=0.5
Exact match

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 5 hits for monomerid = 50071174   

TargetMuscarinic acetylcholine receptor M3(Homo sapiens (Human))
Parke-Davis Pharmaceutical Research

Curated by ChEMBL
LigandPNGBDBM50071174(2-Methyl-9-phenoxy-11,12-dihydro-3H,6aH,13H-6-oxa-...)
Affinity DataIC50:  3.07E+3nMAssay Description:Evaluated for its binding affinity at human muscarinic receptor m3 by the displacement of [3H]NMS binding using membranes from transfected chinese ha...More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetMuscarinic acetylcholine receptor M2(Homo sapiens (Human))
Parke-Davis Pharmaceutical Research

Curated by ChEMBL
LigandPNGBDBM50071174(2-Methyl-9-phenoxy-11,12-dihydro-3H,6aH,13H-6-oxa-...)
Affinity DataIC50:  1.65E+3nMAssay Description:Evaluated for its binding affinity at human muscarinic receptor m2 by displacement of [3H]NMS binding using membranes from transfected chinese hamste...More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetMuscarinic acetylcholine receptor M4(Homo sapiens (Human))
Parke-Davis Pharmaceutical Research

Curated by ChEMBL
LigandPNGBDBM50071174(2-Methyl-9-phenoxy-11,12-dihydro-3H,6aH,13H-6-oxa-...)
Affinity DataIC50:  2.63E+3nMAssay Description:Evaluated for its binding affinity at human muscarinic receptor m4 by the displacement of [3H]NMS binding using membranes from transfected chinese ha...More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetMuscarinic acetylcholine receptor M1(Homo sapiens (Human))
Parke-Davis Pharmaceutical Research

Curated by ChEMBL
LigandPNGBDBM50071174(2-Methyl-9-phenoxy-11,12-dihydro-3H,6aH,13H-6-oxa-...)
Affinity DataIC50:  1.96E+3nMAssay Description:Evaluated for its binding affinity at human muscarinic receptor m1 by displacement of [3H]NMS binding using membranes in transfected chinese hamster ...More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetMuscarinic acetylcholine receptor M5(Homo sapiens (Human))
Parke-Davis Pharmaceutical Research

Curated by ChEMBL
LigandPNGBDBM50071174(2-Methyl-9-phenoxy-11,12-dihydro-3H,6aH,13H-6-oxa-...)
Affinity DataIC50:  2.03E+3nMAssay Description:Evaluated for its binding affinity at human muscarinic receptor m5 by the displacement of [3H]NMS binding using membranes from transfected chinese ha...More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed