BDBM50071299 4-Fluoro-N-(4-{2-[(S)-2-hydroxy-3-(pyridin-3-yloxy)-propylamino]-ethyl}-phenyl)-benzenesulfonamide::CHEMBL64932

SMILES O[C@@H](CNCCc1ccc(NS(=O)(=O)c2ccc(F)cc2)cc1)COc1cccnc1

InChI Key InChIKey=WWPYNKRNJNPFSG-FQEVSTJZSA-N

Data  2 IC50  1 EC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
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Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 3 hits for monomerid = 50071299   

TargetBeta-2 adrenergic receptor(Homo sapiens (Human))
Merck Research Laboratories

Curated by ChEMBL
LigandPNGBDBM50071299(4-Fluoro-N-(4-{2-[(S)-2-hydroxy-3-(pyridin-3-yloxy...)
Affinity DataIC50:  900nMAssay Description:Evaluated for its agonist activity and the binding affinity against human Beta-2 adrenergic receptor in membranes from chinese hamster ovary cellMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetBeta-1 adrenergic receptor(Homo sapiens (Human))
Merck Research Laboratories

Curated by ChEMBL
LigandPNGBDBM50071299(4-Fluoro-N-(4-{2-[(S)-2-hydroxy-3-(pyridin-3-yloxy...)
Affinity DataIC50:  1.00E+3nMAssay Description:Evaluated for its agonist activity and the binding affinity against human Beta-1 adrenergic receptor in membranes from chinese hamster ovary cellMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetBeta-3 adrenergic receptor(Homo sapiens (Human))
Merck Research Laboratories

Curated by ChEMBL
LigandPNGBDBM50071299(4-Fluoro-N-(4-{2-[(S)-2-hydroxy-3-(pyridin-3-yloxy...)
Affinity DataEC50:  18nMAssay Description:Evaluated for Adenylyl cyclase activation as % of the maximal stimulation with isoproterenol at 100 nMMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed