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BDBM50071302 6-(2-Benzyl-thiazol-4-yl)-5-methoxy-pyridine-2-carboxylic acid::CHEMBL70080

SMILES: COc1ccc(nc1-c1csc(Cc2ccccc2)n1)C(O)=O

InChI Key: InChIKey=ILFWEVCRWDNARX-UHFFFAOYSA-N

Data: 1 IC50

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Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 1 hit for monomerid = 50071302   
Target/Host
(Institution)
LigandTarget/Host
Links
Ligand
Links
Trg + Lig
Links
Ki
nM
ΔG°
kcal/mole
IC50
nM
Kd
nM
EC50/IC50
nM
koff
s-1
kon
M-1s-1
pHTemp
°C
Endothelin-converting enzyme 1 (ECE1)


(Homo sapiens (Human))
BDBM50071302
PNG
(6-(2-Benzyl-thiazol-4-yl)-5-methoxy-pyridine-2-car...)
Show SMILES COc1ccc(nc1-c1csc(Cc2ccccc2)n1)C(O)=O
Show InChI InChI=1S/C17H14N2O3S/c1-22-14-8-7-12(17(20)21)19-16(14)13-10-23-15(18-13)9-11-5-3-2-4-6-11/h2-8,10H,9H2,1H3,(H,20,21)
PDB

UniProtKB/SwissProt
UniProtKB/TrEMBL

GoogleScholar
CHEMBL
PC cid
PC sid
UniChem

Similars

Article
PubMed
n/an/a 860n/an/an/an/an/an/a



Warner-Lambert Company

Curated by ChEMBL


Assay Description
Inhibition of human recombinant Endothelin-converting enzyme 1.


Bioorg Med Chem Lett 8: 2117-22 (1999)


Article DOI: 10.1016/s0960-894x(98)00375-8
BindingDB Entry DOI: 10.7270/Q2CC0ZVM
More data for this
Ligand-Target Pair