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BDBM50071757 CHEMBL3410584

SMILES: CCOC(=O)c1sc(Nc2ccc(C)c(C)c2)nc1NC(=O)C1CC1

InChI Key: InChIKey=VRVDTLRDHZLCES-UHFFFAOYSA-N

Data: 1 IC50

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Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 1 hit for monomerid = 50071757   
Target/Host
(Institution)
LigandTarget/Host
Links
Ligand
Links
Trg + Lig
Links
Ki
nM
ΔG°
kcal/mole
IC50
nM
Kd
nM
EC50/IC50
nM
koff
s-1
kon
M-1s-1
pHTemp
°C
Dihydroorotate dehydrogenase


(Homo sapiens (Human))
BDBM50071757
PNG
(CHEMBL3410584)
Show SMILES CCOC(=O)c1sc(Nc2ccc(C)c(C)c2)nc1NC(=O)C1CC1
Show InChI InChI=1S/C18H21N3O3S/c1-4-24-17(23)14-15(20-16(22)12-6-7-12)21-18(25-14)19-13-8-5-10(2)11(3)9-13/h5,8-9,12H,4,6-7H2,1-3H3,(H,19,21)(H,20,22)
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Article
PubMed
n/an/a>1.00E+4n/an/an/an/an/an/a



East China University of Science and Techology

Curated by ChEMBL


Assay Description
Inhibition of human DHODH using dihydroorotate substrate by DCIP assay


J Med Chem 58: 1123-39 (2015)


Article DOI: 10.1021/jm501127s
BindingDB Entry DOI: 10.7270/Q21C1ZK9
More data for this
Ligand-Target Pair