BDBM50072226 3-[4-(3-Phenyl-prop-2-ynyloxy)-[1,2,5]thiadiazol-3-yl]-1-aza-bicyclo[2.2.1]heptane::CHEMBL100163

SMILES C(Oc1nsnc1[C@@H]1CN2CC[C@H]1C2)C#Cc1ccccc1

InChI Key InChIKey=YTPZYIBUXWNHIP-LSDHHAIUSA-N

Data  1 IC50  2 EC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
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Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 3 hits for monomerid = 50072226   

TargetMuscarinic acetylcholine receptor M2(Homo sapiens (Human))
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Curated by ChEMBL
LigandPNGBDBM50072226(3-[4-(3-Phenyl-prop-2-ynyloxy)-[1,2,5]thiadiazol-3...)
Affinity DataEC50:  1.10E+3nMAssay Description:Stimulation of cAMP in CHO cells expressing human m2 receptorMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
LigandPNGBDBM50072226(3-[4-(3-Phenyl-prop-2-ynyloxy)-[1,2,5]thiadiazol-3...)
Affinity DataIC50:  20nMAssay Description:Binding affinity against muscarinic receptor in rat brain membranes using oxotremorine-M as ligandMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetMuscarinic acetylcholine receptor M1(Homo sapiens (Human))
Novo Nordisk

Curated by ChEMBL
LigandPNGBDBM50072226(3-[4-(3-Phenyl-prop-2-ynyloxy)-[1,2,5]thiadiazol-3...)
Affinity DataEC50:  67nMAssay Description:Stimulation of phosphoinositide hydrolysis in A9L cells expressing human m1 receptorMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed