BDBM50072394 1-[3-(1H-4-imidazolyl)-2-(5-oxotetrahydro-1H-2-pyrrolylcarboxamido)propanoyl]tetrahydro-1H-2-pyrrolecarboxamide::A-38579::ABBOTT-38579::PROTIRELIN

SMILES: NC(=O)[C@@H]1CCCN1C(=O)[C@H](Cc1cnc[nH]1)NC(=O)[C@@H]1CCC(=O)N1

InChI Key: InChIKey=XNSAINXGIQZQOO-UHFFFAOYSA-N

Data: 7 KI  6 IC50  12 EC50

Find this compound or compounds like it in BindingDB or PDB:

Substructure Similarity at least:  must be >=0.5 Exact match

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 25 hits for monomerid = 50072394   

Target/Host (Institution)	Ligand	Target/Host Links	Ligand Links	Trg + Lig Links	Ki nM	ΔG° kcal/mole	IC50 nM	Kd nM	EC50 nM	koff s-1	kon M-1s-1	pH	Temp °C
Thyrotropin-releasing hormone receptor (Rat)	BDBM50072394 (PROTIRELIN | ABBOTT-38579 | A-38579 | 1-[3-(1H-4-i...) Show SMILES Show InChI	GoogleScholar	UniChem		n/a	n/a	2.30E+4	n/a	n/a	n/a	n/a	n/a	n/a
TBA									Citation and Details
					More data for this Ligand-Target Pair
Thyrotropin-releasing hormone receptor (Mouse)	BDBM50072394 (PROTIRELIN | ABBOTT-38579 | A-38579 | 1-[3-(1H-4-i...) Show SMILES Show InChI	GoogleScholar	UniChem		n/a	n/a	n/a	n/a	3.10	n/a	n/a	n/a	n/a
TBA									Citation and Details
					More data for this Ligand-Target Pair
Thyrotropin-releasing hormone receptor (Mouse)	BDBM50072394 (PROTIRELIN | ABBOTT-38579 | A-38579 | 1-[3-(1H-4-i...) Show SMILES Show InChI	GoogleScholar	UniChem		n/a	n/a	26	n/a	n/a	n/a	n/a	n/a	n/a
TBA									Citation and Details
					More data for this Ligand-Target Pair
Thyrotropin-releasing hormone receptor (Mouse)	BDBM50072394 (PROTIRELIN | ABBOTT-38579 | A-38579 | 1-[3-(1H-4-i...) Show SMILES Show InChI	GoogleScholar	UniChem		n/a	n/a	n/a	n/a	0.5	n/a	n/a	n/a	n/a
TBA									Citation and Details
					More data for this Ligand-Target Pair
Thyrotropin-releasing hormone receptor (Mouse)	BDBM50072394 (PROTIRELIN | ABBOTT-38579 | A-38579 | 1-[3-(1H-4-i...) Show SMILES Show InChI	GoogleScholar	UniChem		n/a	n/a	n/a	n/a	1	n/a	n/a	n/a	n/a
TBA									Citation and Details
					More data for this Ligand-Target Pair
Thyrotropin-releasing hormone receptor (Mouse)	BDBM50072394 (PROTIRELIN | ABBOTT-38579 | A-38579 | 1-[3-(1H-4-i...) Show SMILES Show InChI	GoogleScholar	UniChem		n/a	n/a	7	n/a	n/a	n/a	n/a	n/a	n/a
TBA									Citation and Details
					More data for this Ligand-Target Pair
Thyrotropin-releasing hormone receptor (Mouse)	BDBM50072394 (PROTIRELIN | ABBOTT-38579 | A-38579 | 1-[3-(1H-4-i...) Show SMILES Show InChI	GoogleScholar	UniChem		n/a	n/a	n/a	n/a	3.20	n/a	n/a	n/a	n/a
TBA									Citation and Details
					More data for this Ligand-Target Pair
Thyrotropin-releasing hormone receptor (Mouse)	BDBM50072394 (PROTIRELIN | ABBOTT-38579 | A-38579 | 1-[3-(1H-4-i...) Show SMILES Show InChI	GoogleScholar	UniChem		n/a	n/a	n/a	n/a	0.520	n/a	n/a	n/a	n/a
TBA									Citation and Details
					More data for this Ligand-Target Pair
Thyrotropin-releasing hormone receptor (Mouse)	BDBM50072394 (PROTIRELIN | ABBOTT-38579 | A-38579 | 1-[3-(1H-4-i...) Show SMILES Show InChI	GoogleScholar	UniChem		n/a	n/a	n/a	n/a	1	n/a	n/a	n/a	n/a
TBA									Citation and Details
					More data for this Ligand-Target Pair
Thyrotropin-releasing hormone receptor (Mouse)	BDBM50072394 (PROTIRELIN | ABBOTT-38579 | A-38579 | 1-[3-(1H-4-i...) Show SMILES Show InChI	GoogleScholar	UniChem		n/a	n/a	2.60	n/a	n/a	n/a	n/a	n/a	n/a
TBA									Citation and Details
					More data for this Ligand-Target Pair
Thyrotropin-releasing hormone receptor (Mouse)	BDBM50072394 (PROTIRELIN | ABBOTT-38579 | A-38579 | 1-[3-(1H-4-i...) Show SMILES Show InChI	GoogleScholar	UniChem		n/a	n/a	7	n/a	n/a	n/a	n/a	n/a	n/a
TBA									Citation and Details
					More data for this Ligand-Target Pair
Thyrotropin-releasing hormone receptor (Mouse)	BDBM50072394 (PROTIRELIN | ABBOTT-38579 | A-38579 | 1-[3-(1H-4-i...) Show SMILES Show InChI	GoogleScholar	UniChem		n/a	n/a	n/a	n/a	0.680	n/a	n/a	n/a	n/a
TBA									Citation and Details
					More data for this Ligand-Target Pair
Thyrotropin-releasing hormone receptor (Rat)	BDBM50072394 (PROTIRELIN | ABBOTT-38579 | A-38579 | 1-[3-(1H-4-i...) Show SMILES Show InChI	GoogleScholar	UniChem		n/a	n/a	23	n/a	n/a	n/a	n/a	n/a	n/a
TBA									Citation and Details
					More data for this Ligand-Target Pair
Thyrotropin-releasing hormone receptor (Rat)	BDBM50072394 (PROTIRELIN | ABBOTT-38579 | A-38579 | 1-[3-(1H-4-i...) Show SMILES Show InChI	GoogleScholar	UniChem		n/a	n/a	n/a	n/a	3	n/a	n/a	n/a	n/a
TBA									Citation and Details
					More data for this Ligand-Target Pair
Thyrotropin-releasing hormone receptor (Human)	BDBM50072394 (PROTIRELIN | ABBOTT-38579 | A-38579 | 1-[3-(1H-4-i...) Show SMILES Show InChI	GoogleScholar	UniChem		n/a	n/a	n/a	n/a	3	n/a	n/a	n/a	n/a
TBA									Citation and Details
					More data for this Ligand-Target Pair
Thyrotropin-releasing hormone receptor (Rat)	BDBM50072394 (PROTIRELIN | ABBOTT-38579 | A-38579 | 1-[3-(1H-4-i...) Show SMILES Show InChI	GoogleScholar	UniChem		n/a	n/a	n/a	n/a	3	n/a	n/a	7.8	n/a
TBA									Citation and Details
					More data for this Ligand-Target Pair
Thyrotropin-releasing hormone receptor (Rat)	BDBM50072394 (PROTIRELIN | ABBOTT-38579 | A-38579 | 1-[3-(1H-4-i...) Show SMILES Show InChI	GoogleScholar	UniChem		n/a	n/a	n/a	n/a	3	n/a	n/a	7.8	n/a
TBA									Citation and Details
					More data for this Ligand-Target Pair
Thyrotropin-releasing hormone receptor (Mouse)	BDBM50072394 (PROTIRELIN | ABBOTT-38579 | A-38579 | 1-[3-(1H-4-i...) Show SMILES Show InChI	GoogleScholar	UniChem		n/a	n/a	n/a	n/a	0.490	n/a	n/a	n/a	n/a
TBA									Citation and Details
					More data for this Ligand-Target Pair
Thyrotropin-releasing hormone receptor (Mouse)	BDBM50072394 (PROTIRELIN | ABBOTT-38579 | A-38579 | 1-[3-(1H-4-i...) Show SMILES Show InChI	GoogleScholar	UniChem		10	n/a	n/a	n/a	n/a	n/a	n/a	n/a	n/a
TBA									Citation and Details
					More data for this Ligand-Target Pair
Thyrotropin-releasing hormone receptor (Rat)	BDBM50072394 (PROTIRELIN | ABBOTT-38579 | A-38579 | 1-[3-(1H-4-i...) Show SMILES Show InChI	GoogleScholar	UniChem		10	n/a	n/a	n/a	n/a	n/a	n/a	n/a	n/a
TBA									Citation and Details
					More data for this Ligand-Target Pair
Thyrotropin-releasing hormone receptor (Rat)	BDBM50072394 (PROTIRELIN | ABBOTT-38579 | A-38579 | 1-[3-(1H-4-i...) Show SMILES Show InChI	GoogleScholar	UniChem		10	n/a	n/a	n/a	n/a	n/a	n/a	7.4	n/a
TBA									Citation and Details
					More data for this Ligand-Target Pair
Thyrotropin-releasing hormone receptor (Human)	BDBM50072394 (PROTIRELIN | ABBOTT-38579 | A-38579 | 1-[3-(1H-4-i...) Show SMILES Show InChI	GoogleScholar	UniChem		20	n/a	n/a	n/a	n/a	n/a	n/a	n/a	n/a
TBA									Citation and Details
					More data for this Ligand-Target Pair
Thyrotropin-releasing hormone receptor (Rat)	BDBM50072394 (PROTIRELIN | ABBOTT-38579 | A-38579 | 1-[3-(1H-4-i...) Show SMILES Show InChI	GoogleScholar	UniChem		20	n/a	n/a	n/a	n/a	n/a	n/a	7.4	n/a
TBA									Citation and Details
					More data for this Ligand-Target Pair
Thyrotropin-releasing hormone receptor (Mouse)	BDBM50072394 (PROTIRELIN | ABBOTT-38579 | A-38579 | 1-[3-(1H-4-i...) Show SMILES Show InChI	GoogleScholar	UniChem		23	n/a	n/a	n/a	n/a	n/a	n/a	n/a	n/a
TBA									Citation and Details
					More data for this Ligand-Target Pair
Thyrotropin-releasing hormone receptor (Rat)	BDBM50072394 (PROTIRELIN | ABBOTT-38579 | A-38579 | 1-[3-(1H-4-i...) Show SMILES Show InChI	GoogleScholar	UniChem		42	n/a	n/a	n/a	n/a	n/a	n/a	n/a	n/a
TBA									Citation and Details
					More data for this Ligand-Target Pair