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BDBM50072890 3-Benzhydrylidene-1-{(Z)-4-[4-(2-methoxy-phenyl)-piperazin-1-yl]-but-2-enyl}-pyrrolidine-2,5-dione::CHEMBL145329

SMILES: [#6]-[#8]-c1ccccc1-[#7]-1-[#6]-[#6]-[#7](-[#6]\[#6]=[#6]/[#6]-[#7]-2-[#6](=O)-[#6]\[#6](=[#6](/c3ccccc3)-c3ccccc3)-[#6]-2=O)-[#6]-[#6]-1

InChI Key: InChIKey=UTKABUUGVVEZMS-KHPPLWFESA-N

Data: 1 KI

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Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 1 hit for monomerid = 50072890   
Target/Host
(Institution)
LigandTarget/Host
Links
Ligand
Links
Trg + Lig
Links
Ki
nM
ΔG°
kcal/mole
IC50
nM
Kd
nM
EC50/IC50
nM
koff
s-1
kon
M-1s-1
pHTemp
°C
Serotonin (5-HT) receptor


(Rattus norvegicus (rat))
BDBM50072890
PNG
(3-Benzhydrylidene-1-{(Z)-4-[4-(2-methoxy-phenyl)-p...)
Show SMILES COc1ccccc1N1CCN(C\C=C/CN2C(=O)CC(=C(c3ccccc3)c3ccccc3)C2=O)CC1
Show InChI InChI=1S/C32H33N3O3/c1-38-29-17-9-8-16-28(29)34-22-20-33(21-23-34)18-10-11-19-35-30(36)24-27(32(35)37)31(25-12-4-2-5-13-25)26-14-6-3-7-15-26/h2-17H,18-24H2,1H3/b11-10-
KEGG

UniProtKB/SwissProt

GoogleScholar
CHEMBL
PC cid
PC sid
UniChem

Similars

Article
PubMed
237n/an/an/an/an/an/an/an/a



Universidad Complutense

Curated by ChEMBL


Assay Description
Binding affinity at 5-hydroxytryptamine 1A (5-HT1A) receptor in rat cerebral cortex using [3H]-8-OH-DPAT as radioligand


J Med Chem 42: 36-49 (1999)


Article DOI: 10.1021/jm980285e
BindingDB Entry DOI: 10.7270/Q2B27TFT
More data for this
Ligand-Target Pair