BDBM50072974 (1,2,3,4-Tetrahydro-isoquinolin-7-yl)-methanol::CHEMBL286495

SMILES OCc1ccc2CCNCc2c1

InChI Key InChIKey=RAUHFTOXJZRVIJ-UHFFFAOYSA-N

Data  3 KI

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
Find this compound or compounds like it in BindingDB:
   Substructure
Similarity at least:  must be >=0.5
Exact match

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 3 hits for monomerid = 50072974   

LigandPNGBDBM50072974((1,2,3,4-Tetrahydro-isoquinolin-7-yl)-methanol | C...)
Affinity DataKi:  3.55E+3nMAssay Description:Inhibition of [3H]clonidine binding to the rat alpha-2-adrenoceptorMore data for this Ligand-Target Pair
In Depth
Date in BDB:
10/19/2018
Entry Details Article
PubMed
TargetPhenylethanolamine N-methyltransferase(Bovine)
University of Kansas

Curated by ChEMBL
LigandPNGBDBM50072974((1,2,3,4-Tetrahydro-isoquinolin-7-yl)-methanol | C...)
Affinity DataKi:  6.94E+3nMAssay Description:Inhibitory activity against bovine adrenal phenylethanolamine N-methyl-transferase (PNMT)More data for this Ligand-Target Pair
In Depth
Date in BDB:
10/19/2018
Entry Details Article
PubMed
TargetPhenylethanolamine N-methyltransferase(Bovine)
University of Kansas

Curated by ChEMBL
LigandPNGBDBM50072974((1,2,3,4-Tetrahydro-isoquinolin-7-yl)-methanol | C...)
Affinity DataKi:  1.10E+4nMAssay Description:In vitro inhibitory activity against bovine adrenal phenylethanolamine N-methyl-transferase (PNMT)More data for this Ligand-Target Pair
In Depth
Date in BDB:
11/10/2012
Entry Details Article
PubMed