BDBM50073272 4-Methyl-7-[3-(4-phenyl-piperazin-1-yl)-propoxy]-chromen-2-one::CHEMBL52096

SMILES Cc1cc(=O)oc2cc(OCCCN3CCN(CC3)c3ccccc3)ccc12

InChI Key InChIKey=ZYBLSQVXWVJACW-UHFFFAOYSA-N

Data  6 KI

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
Find this compound or compounds like it in BindingDB:
   Substructure
Similarity at least:  must be >=0.5
Exact match

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 6 hits for monomerid = 50073272   

Target5-hydroxytryptamine receptor 1A(Rattus norvegicus (rat))
University Of Vigo

Curated by ChEMBL
LigandPNGBDBM50073272(4-Methyl-7-[3-(4-phenyl-piperazin-1-yl)-propoxy]-c...)
Affinity DataKi:  5.5nMAssay Description:Compound was measured for the inhibition of [3H]-8-OH-DPAT binding to rat hippocampus membrane (5-HT1A receptor)More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetD(2) dopamine receptor(Homo sapiens (Human))
Huazhong University Of Science And Technology

Curated by ChEMBL
LigandPNGBDBM50073272(4-Methyl-7-[3-(4-phenyl-piperazin-1-yl)-propoxy]-c...)
Affinity DataKi:  11nMAssay Description:Binding affinity to dopamine D2 receptor (unknown origin)More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetD(2) dopamine receptor(Homo sapiens (Human))
Huazhong University Of Science And Technology

Curated by ChEMBL
LigandPNGBDBM50073272(4-Methyl-7-[3-(4-phenyl-piperazin-1-yl)-propoxy]-c...)
Affinity DataKi:  14nMAssay Description:Compound was measured for the binding affinity in homogenated mouse fibroblast (LTK) cells transfected with human Dopamine receptor D2A using [3H]-ra...More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetD(2) dopamine receptor(Rattus norvegicus (rat))
University Of Santiago

Curated by ChEMBL
LigandPNGBDBM50073272(4-Methyl-7-[3-(4-phenyl-piperazin-1-yl)-propoxy]-c...)
Affinity DataKi:  46nMAssay Description:Binding affinity towards Dopamine receptor D2 in rat frontal striatum using [3H]spiperoneMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetD(3) dopamine receptor(Homo sapiens (Human))
University Of Vigo

Curated by ChEMBL
LigandPNGBDBM50073272(4-Methyl-7-[3-(4-phenyl-piperazin-1-yl)-propoxy]-c...)
Affinity DataKi:  74nMAssay Description:Compound was measured for the binding affinity in chinese hamster ovary (CHO) cells transfected with human Dopamine receptor D3 using [3H]-raclopride...More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
Target5-hydroxytryptamine receptor 2A(Rattus norvegicus (rat))
University Of Santiago

Curated by ChEMBL
LigandPNGBDBM50073272(4-Methyl-7-[3-(4-phenyl-piperazin-1-yl)-propoxy]-c...)
Affinity DataKi:  933nMAssay Description:Binding affinity towards 5-hydroxytryptamine 2A receptor using [3H]ketanserinMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed