BDBM50073434 (R)-8-Methyl-2,3-diphenyl-8-aza-bicyclo[3.2.1]octane::CHEMBL3084336

SMILES [H][C@@]12CC[C@@]([H])([C@H]([C@@H](C1)c1ccccc1)c1ccccc1)N2C

InChI Key

Data  6 IC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
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Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 6 hits for monomerid = 50073434   

TargetSodium-dependent dopamine transporter(Rat)
Research Triangle Institute

Curated by ChEMBL
LigandPNGBDBM50073434((R)-8-Methyl-2,3-diphenyl-8-aza-bicyclo[3.2.1]octa...)
Affinity DataIC50: 12.6nMAssay Description:Inhibitory activity against radioligand [3H]WIN-35428 binding at the dopamine transporterMore data for this Ligand-Target Pair
In Depth
Date in BDB:
9/29/2012
Entry Details Article
PubMed
TargetSodium-dependent dopamine transporter(Rat)
Research Triangle Institute

Curated by ChEMBL
LigandPNGBDBM50073434((R)-8-Methyl-2,3-diphenyl-8-aza-bicyclo[3.2.1]octa...)
Affinity DataIC50: 13nMAssay Description:Inhibitory activity against radioligand [3H]WIN-35428 binding at the dopamine transporterMore data for this Ligand-Target Pair
In Depth
Date in BDB:
9/29/2012
Entry Details Article
PubMed
TargetTransporter(Rat)
Research Triangle Institute

Curated by ChEMBL
LigandPNGBDBM50073434((R)-8-Methyl-2,3-diphenyl-8-aza-bicyclo[3.2.1]octa...)
Affinity DataIC50: 690nMAssay Description:Inhibitory activity against radioligand [3H]nisoxetine binding at the norepinephrine transporterMore data for this Ligand-Target Pair
In Depth
Date in BDB:
9/29/2012
Entry Details Article
PubMed
TargetTransporter(Rat)
Research Triangle Institute

Curated by ChEMBL
LigandPNGBDBM50073434((R)-8-Methyl-2,3-diphenyl-8-aza-bicyclo[3.2.1]octa...)
Affinity DataIC50: 917nMAssay Description:Inhibitory activity against radioligand [3H]nisoxetine binding at the norepinephrine transporterMore data for this Ligand-Target Pair
In Depth
Date in BDB:
9/29/2012
Entry Details Article
PubMed
TargetSodium-dependent serotonin transporter(Rat)
Research Triangle Institute

Curated by ChEMBL
LigandPNGBDBM50073434((R)-8-Methyl-2,3-diphenyl-8-aza-bicyclo[3.2.1]octa...)
Affinity DataIC50: 2.11E+4nMAssay Description:Inhibitory activity against radioligand [3H]paroxetine binding at the serotonin transporterMore data for this Ligand-Target Pair
In Depth
Date in BDB:
9/29/2012
Entry Details Article
PubMed
TargetSodium-dependent serotonin transporter(Rat)
Research Triangle Institute

Curated by ChEMBL
LigandPNGBDBM50073434((R)-8-Methyl-2,3-diphenyl-8-aza-bicyclo[3.2.1]octa...)
Affinity DataIC50: 2.11E+4nMAssay Description:Inhibitory activity against radioligand [3H]paroxetine binding at the serotonin transporterMore data for this Ligand-Target Pair
In Depth
Date in BDB:
9/29/2012
Entry Details Article
PubMed