BDBM50073559 1-[4-(4-Amino-6,7-dimethoxy-quinazolin-2-yl)-piperazin-1-yl]-2-(2-isopropyl-6-methoxy-phenoxy)-propan-1-one::CHEMBL136458
SMILES COc1cc2nc(nc(N)c2cc1OC)N1CCN(CC1)C(=O)C(C)Oc1c(OC)cccc1C(C)C
InChI Key InChIKey=XLJAXHKXAQXROY-UHFFFAOYSA-N
Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB
Found 6 hits for monomerid = 50073559
Affinity DataKi: 14.7nMAssay Description:The binding affinity of the compound was determined towards Alpha-1B adrenergic receptor in the COS cell line.More data for this Ligand-Target Pair
Affinity DataKi: 156nMAssay Description:The binding affinity of the compound was determined towards Alpha-1A adrenergic receptor in the COS cell line.More data for this Ligand-Target Pair
Affinity DataKi: 1.11E+3nMAssay Description:The binding affinity of the compound was determined towards Alpha-1C adrenergic receptor in the COS cell line.More data for this Ligand-Target Pair
Affinity DataIC50: >1.00E+3nMAssay Description:Inhibitory concentration against 5-hydroxytryptamine 1A receptor (Inactive at >1000 nM concentration)More data for this Ligand-Target Pair
Affinity DataIC50: >1.00E+3nMAssay Description:Inhibitory concentration against 5-hydroxytryptamine 2A receptor (Inactive at >1000 nM concentration)More data for this Ligand-Target Pair
Affinity DataIC50: >1.00E+3nMAssay Description:Inhibitory concentration against Dopamine receptor D2 (Inactive at >1000 nM concentration)More data for this Ligand-Target Pair