BDBM50073568 6,7-Dimethoxy-2-piperazin-1-yl-quinazolin-4-ylamine::Aminodimethoxyquinazolinylpiperazine (piperazine derivative of terazosin)::CHEMBL1226::cid_616267

SMILES: COc1cc2c(cc1OC)nc(nc2N)N3CCNCC3

InChI Key: InChIKey=APKHJGDGWQDBGM-UHFFFAOYSA-N

Data: 9 IC50  1 EC50

PDB links: 1 PDB ID matches this monomer.

Find this compound or compounds like it in BindingDB or PDB:

Substructure Similarity at least:  must be >=0.5 Exact match

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 10 hits for monomerid = 50073568   

Target/Host (Institution)	Ligand	Target/Host Links	Ligand Links	Trg + Lig Links	Ki nM	ΔG° kcal/mole	IC50 nM	Kd nM	EC50 nM	koff s-1	kon M-1s-1	pH	Temp °C
Ubiquitin-conjugating enzyme E2 N (Human)	BDBM50073568 (cid_616267 | CHEMBL1226 | 6,7-Dimethoxy-2-piperazi...) Show SMILES Show InChI	GoogleScholar	UniChem		n/a	n/a	1.50E+3	n/a	n/a	n/a	n/a	n/a	n/a
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Ubiquitin-conjugating enzyme E2 N (Human)	BDBM50073568 (cid_616267 | CHEMBL1226 | 6,7-Dimethoxy-2-piperazi...) Show SMILES Show InChI	GoogleScholar	UniChem		n/a	n/a	873	n/a	n/a	n/a	n/a	n/a	n/a
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Bcl-2-related protein A1 (Mouse)	BDBM50073568 (cid_616267 | CHEMBL1226 | 6,7-Dimethoxy-2-piperazi...) Show SMILES Show InChI	GoogleScholar	UniChem		n/a	n/a	1.11E+4	n/a	n/a	n/a	n/a	n/a	n/a
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Apoptotic protease-activating factor 1 (Human)	BDBM50073568 (cid_616267 | CHEMBL1226 | 6,7-Dimethoxy-2-piperazi...) Show SMILES Show InChI	GoogleScholar	UniChem		n/a	n/a	3.15E+4	n/a	n/a	n/a	n/a	n/a	n/a
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Apoptotic protease-activating factor 1 (Human)	BDBM50073568 (cid_616267 | CHEMBL1226 | 6,7-Dimethoxy-2-piperazi...) Show SMILES Show InChI	GoogleScholar	UniChem		n/a	n/a	>1.00E+5	n/a	n/a	n/a	n/a	n/a	n/a
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Caspase-9 (Human)	BDBM50073568 (cid_616267 | CHEMBL1226 | 6,7-Dimethoxy-2-piperazi...) Show SMILES Show InChI	GoogleScholar	UniChem		n/a	n/a	>1.00E+5	n/a	n/a	n/a	n/a	n/a	n/a
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Beta-2 adrenergic receptor (Human)	BDBM50073568 (cid_616267 | CHEMBL1226 | 6,7-Dimethoxy-2-piperazi...) Show SMILES Show InChI	GoogleScholar	UniChem		n/a	n/a	n/a	n/a	8.61E+3	n/a	n/a	n/a	n/a
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5-hydroxytryptamine receptor 2A (Rat)	BDBM50073568 (cid_616267 | CHEMBL1226 | 6,7-Dimethoxy-2-piperazi...) Show SMILES Show InChI	GoogleScholar	UniChem		n/a	n/a	>1.00E+3	n/a	n/a	n/a	n/a	n/a	n/a
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D(2) dopamine receptor (Rat)	BDBM50073568 (cid_616267 | CHEMBL1226 | 6,7-Dimethoxy-2-piperazi...) Show SMILES Show InChI	GoogleScholar	UniChem		n/a	n/a	>1.00E+3	n/a	n/a	n/a	n/a	n/a	n/a
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5-hydroxytryptamine receptor 1A (Rat)	BDBM50073568 (cid_616267 | CHEMBL1226 | 6,7-Dimethoxy-2-piperazi...) Show SMILES Show InChI	GoogleScholar	UniChem		n/a	n/a	>1.00E+3	n/a	n/a	n/a	n/a	n/a	n/a
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