BDBM50073897 1-Mercaptomethyl-4-trifluoromethyl-cyclohexanecarboxylic acid ((S)-1-methylcarbamoyl-2-phenyl-ethyl)-amide::CHEMBL293017

SMILES CNC(=O)[C@H](Cc1ccccc1)NC(=O)[C@]1(CS)CC[C@@H](CC1)C(F)(F)F

InChI Key InChIKey=RLWIZPNGKRUYBT-RLFYNMQTSA-N

Data  3 IC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
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Exact match

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 3 hits for monomerid = 50073897   

TargetMetalloproteinase inhibitor 3(Rattus norvegicus)
Novartis Biomedical Research Institute

Curated by ChEMBL
LigandPNGBDBM50073897(1-Mercaptomethyl-4-trifluoromethyl-cyclohexanecarb...)
Affinity DataIC50:  4.47E+3nMAssay Description:In vitro inhibitory activity against matrix metalloproteinase-3More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetMatrix metalloproteinase-9(Rattus norvegicus (Rat))
Novartis Biomedical Research Institute

Curated by ChEMBL
LigandPNGBDBM50073897(1-Mercaptomethyl-4-trifluoromethyl-cyclohexanecarb...)
Affinity DataIC50:  108nMAssay Description:In vitro inhibitory activity against matrix metalloproteinase-9More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetInterstitial collagenase(Homo sapiens (Human))
Novartis Biomedical Research Institute

Curated by ChEMBL
LigandPNGBDBM50073897(1-Mercaptomethyl-4-trifluoromethyl-cyclohexanecarb...)
Affinity DataIC50:  669nMAssay Description:In vitro inhibitory activity against matrix metalloproteinase 1More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed